Caring for Skin: Your Eye Skin with Neuropeptides

Although your skin is technically one large organ, not all parts of it have the same properties or needs. Differences in thickness, density of hair follicles, and oil gland activity means you can’t treat every inch of skin the same.

In particular, the skin around your eyes is especially sensitive and delicate. To stay healthy and beautiful, it needs special attention and care at every age.

This article will discuss:

In order to properly care for the skin in the eye area, it helps to understand the unique anatomy of this area.

The structures surrounding the eye are called the eye adnexa; they consist of:

  • Orbital fascia
  • Ocular muscles
  • Eyelids
  • Tunica conjunctiva
  • Lacrimal apparatus, or tear ducts

Eyelid skin is composed of several layers. The deepest layer rests on top of the orbicularis muscle, the muscle that controls movement of the eyelid. It consists of a thin layer of fascia, a soft tissue element of the connective tissue system found throughout the human body. Next comes the dermis which is made up of threadlike proteins and bunches of elastin and collagen. Finally the top layer, or epidermis, gives skin its color, texture, and overall appearance.

Eyes are one of the first places to show aging, partly because the skin around the eyes is so thin. However, there are methods to protect the skin and treat both wrinkles and dark circles. Your best weapons against eye area aging are to use a daily eye lift cream to lock in moisture and to protect the area with sunscreen.

When choosing an eye area treatment, it is a good idea to look for one does not contain irritating ingredients or oils. The reduces the likelihood of clogged glands, styes, and other ocular problems. Products packaged in pumps rather than jars are preferable because the minimize the potential for contamination from your fingers.

Perricone MD‘s exclusive line of Neuropeptide products includes the Neuropeptide cream. It nourishes the skin around the eyes with alpha lipoic acid and DMAE. These ingredients help to firm the skin, minimize dark circles, and reduce the appearance of puffiness and wrinkles.

Other than treating it with quality products as a part of your daily routine, there are lifestyle steps you can take to protect the skin around your eyes:

  • Drink plenty of water — This helps keep all your skin hydrated and aids in the maintenance of elasticity.
  • Avoid smoking — Nicotine constricts the blood vessels, even under the eyes. This can lead to nutrient-deprived skin and decreased collagen production.
  • Monitor sun exposure — Overexposure to UV rays can lead to uneven pigmentation caused by abnormal melanocyte (pigment-producer) maturation. Wearing UV protective sunglasses keeps the damaging rays away from the skin and prevents squinting which can itself cause wrinkles.
  • Get enough rest — To reduce dark circles and puffiness, sleep at least seven to eight hours every night. Also, try sleeping with your head slightly elevated. This fights helps prevent fluid from collecting in your lower eyelids.
  • Be gentle — The skin around the eye requires delicate handling. Use cotton balls when removing make-up as to avoid pulling or tugging at the skin. When applying eye cream, use your ring finger in order to exert less pressure on the area.

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10 Comments • Please comment below


  1. I have tried treatments, serums, creams and nothing seems to help! I am going to be 44 and have great skin except for what I inherited around my eyes!!! My eyelids are drooping, I have crows feet and sagging underneath my eyes – oh did I mention crinkling too? It’s terrible!! I feel like I am 30 until I laugh and then I look like I’m 60… Please help!!!! Carie:)

  2. I’ve always had dark circles and puffy eyes, but now as I get older, the wrinkles are coming in and I think they are aging my face way more than I want, so this would be great.

  3. I have tried many of Dr. Perricone’s products and bought his diet book for great looking skin. The eye cream with Neuropeptides is something I am very interested in and would benefit my creapy delicate skin around my eyes and my dark circles. Thank you for making such wonderful products that work for me !

  4. I have tried your other eye treatment but this sounds like it would be more beneficial for the aging skin and dark circles I have around my eyes. As a 42 yr old mom of a 2 yr old I would love to try this one step solution.

  5. I’m 50. I wake up with puffiness under eyes and the wrinkles there seem to be getting worse. I don’t smoke but crows feet have started. My upper lids droop and I don’t wear eyeshadow anymore as you couldn’t see it anyhow.My blue eyes look smaller because of this. No problem with dark circles. My under eye area is actually lighter and is difficult to cover with concealer. Hope to try product that can help with any/all of this.

  6. Could this be the answer to my wrinkles around my eyes and occasional puffiness? Would love to try this product to find out. I need something that works.

  7. I live in Wisconsin where you never know what the weather brings until you wake up in the morning. I have tried several products that have promised to make the fine lines and wrinkels disappear but the only thing that disappeared was my money. I am turning 46 this year with wondering what happened to my 21 year old complexion. These are great deals and products that Dr. Perricone is offering to us and I would love to become a tester of the Dr.’s products and give feedback that I am sure is going to be positive. Thank you for your time and consideration.

  8. I am 52, my skin is in good shape, I use of few of Dr. Perricone proucts but none yet on my eyes.
    I have fine lines and crepiness and some sagging.
    This looks like the best product so far after much much reading.
    I’d love to try this.

  9. Would love to try this product. I’m in my mid-thirties, and would love to keep my skin looking young and healthy. I know that the eye area is the first to get crow’s feet, and I definitely want to prevent this.

  10. My skin around the eyes is in definite need of help! It has begun to sag ever so slightly…… It would be great if this could help firm that area up.