Perricone MD Serum Prep: Deep Wrinkle Serum for Mature Skin

clinical creations

Wrinkles may be a common part of aging, but that does not mean there is nothing that can be done to treat them. Some think the only way to firm the skin and diminish the signs of wrinkles and fine lines is to go under the knife, but there are many safer, less invasive options available, such as a deep wrinkle serum.

In order to know how to treat wrinkles, it is best to understand how they occur.

Wrinkles occur because as skin ages, it loses collagen and elastin, which are proteins that keep the skin stretchable and tight. The decrease in these proteins causes the skin to be less able to resume its shape after stretching or contracting. This means that the skin is more likely to develop creases, wrinkles, and a sagging appearance after repeated facial movements.

Fortunately there are several ways to reduce wrinkles:

  • Avoid the sun: Researchers have found that sun exposure is more important than heredity in causing wrinkles
  • Don’t smoke: Cigarette smoke releases an enzyme that breaks down collagen and elastin
  • Get adequate sleep: When you don’t get enough sleep, the body produces excess cortisol, a hormone that breaks down skin cells
  • Eat a non-inflammatory diet: Eating healthy fats, low-glycemic carbohydrates, high-quality protein, and fruits and vegetables helps keep cells healthier longer

In addition to these precautions, consider an anti-aging regimen that includes topical treatments. One effective topical treatment is the Perricone MD Serum Prep. The Serum Prep is a deep wrinkle serum, that if applied twice a day to the face and neck, will not only help firm, tone, and refine the skin’s texture, but hydrate and repair damaged skin as well. Like many of the best topical treatments, the Serum Prep is formulated with the natural sciences DMAE and Phospholipids.

What are DMAE and Phospholipids?

DMAE, short for dimethylaminoethanol, is responsible for the creation of acetylcholine, which is involved with muscle activity, and therefore firms the skin by working to stimulate increased tone in the muscles behind the face.

Phospholipids replaces the natural protective layer around the skin that is worn away from damaging environmental factors such as the sun, wind, and pollution.

The Doctor is "in" on Facebook.

11 Comments • Please comment below


  1. [...] best way to treat a workaholic’s deep wrinkles is with an anti wrinkle serum. And now that you know your skin won’t benefit from the indoors, be sure to get creams with SPF [...]

  2. [...] Along with eye areas giving away age, forehead wrinkles are very telling of mature skin. People may start to see forehead wrinkles also by their 20’s. Luckily, these wrinkles can be masked by using a strong deep wrinkle cream. [...]

  3. I would like to try this product and become a tester. I am 71 years old, and sensitive and sincere about my skin.

    Thank you!

  4. when you think of fighting the 10 signs of aging, I already have all of them. I’m 46 years old and have the premature aging of a woman of 60. I need this product to reverse these signs and return my skin to its natural state for my age zone. I have been eating healthy and exercising for the reversal of mother nature, and now I need to fight the free radicals of aging with this wonderful product.

  5. I have been using the Made from Earth Olive Night Creme for the last 4-5 years as my night cream. I am 42 years old and have virtually no wrinkles. I always moisten my face first with a spritz of water then emulsify the Olive Night Creme in the palm of my hand. It spreads easier all over face and neck. I also like to put it in my hair (small amount) after washing while still wet, then it combs out easily and makes my curls softer and shinier. It works great on dry hair (tiny amount rubbed in palms of hands) as defrizzer and shine booster. I also enjoy it as a hand/cuticle cream and lip balm. you can also use it as a female moisturizer or lubricant.

    I love that it has no artificial ingredients or preservatives. Remember, honey is naturally antibacterial. I am sold for life! It is expensive at whole foods, but I sometimes see a deal on their website. I love this stuff and the jar does last quite a long time.

  6. I am interested in doing just about anything to reduce the aging process.

  7. Greetings, OK I’m reading these wonderful comments on Perricone’s and I really want in on this!!! I’m coming up on the ripe age of 50 and going through the early stages of menopause GRRRRR but this is life.I have my son’s wedding this year my 35th class reunion lost 50 pounds now I just need my face to look tight & firm with alot less wrinkles.So PLEASE help me look GREAT. Thank you so much

  8. I am a 40 year old mother of 3, and I’ve been using the Made from Earth Vitamin Enhanced Face Firming Serum since receiving a free sample in the mail when I purchased their body lotion several years ago. I have been using it faithfully 2x per day ever since… and I have NO wrinkles…. I’ve been taking my 13 year old son to the same restaurant each week for several months, and on my last visit the hostess said, “I’ve been meaning to ask you, is he your brother or your son. You look so young.”

    I’ve been using it for as long as I can remember – it’s the only one I can use on my face without an allergic reaction. I think my nice complexion is attributable to my daily regimen, including these Made from Earth products. They’re wonderful!!

  9. I won this on Perricone’s Facebook and just received it today, and I have to say it is a very much welcomed gift! I am 51 and am going through the early stages of menopause and lately my skin has been going through a lot changes. I have always had combination skin but now have developed dry patchy areas, redness, uneven skin tone and fine lines and dryness under my eyes. I plan on using this tonight after washing my face and everyday after that. Thank you so much for this!

  10. [...] Perricone’s Serum Prep is a topical cream formulated with DMAE and Phospholipids to reduce the appearance of fine lines [...]

  11. I rgot a sample of this with my light therepy and fell in love with it. I found it to be very refeshing to my skin.