Perricone MD – Perricone DMAE Supplements

With the brain-beauty connection in mind, Perricone DMAE is a supplement that improves skin’s appearance and enhances cognitive function.

Comment on Perricone DMAE for a chance to win it!

Find out more about Perricone DMAE:

Key Sciences and Benefits of Perricone DMAE

Watch Dr. Perricone discuss DMAE as supplements:

DMAE’s benefits include:

  • Re-contours improving skin losing elasticity
  • Lifts, tightens, and tones skin
  • Minimizes fine lines and wrinkles

Try Perricone for as little at $10.

Ingredients and Application of Perricone DMAE


  • DMAE 75 mg per serving
  • Tocotrienols Complex 5 mg per serving
  • Other: Dicalcium phosphate, gelatin, cellulose, magnesium stearate, and silica

Serving Size:
1 Capsule

Servings Per Container: 60

Application: Dr. Perricone recommends taking 2 capsules daily with meals.

Recent Reviews

Tightens and tones – “I love this product. I am over 40 yrs biologically and feel and look like i am 30. Beauty is an inside job and these supplements truly make the difference.” —From Perricone MD

Helped skin texture - “I took this supplement as directed for 30 days and saw a difference. I’m reordering cause I think it works.” —From Amazon

Definitely enhances facial contours - “I am 53 but have none of the sagging my friends my age experience. They do not believe it is because of the DMAE but I quit for 90 days to prove my point and began to see sagging. Went back on it and would not be without it.” —From Perricone MD

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119 Comments • Please comment below


  1. Hi, I am 47 years old. No wrinkles yet, but am noticing my first line on my upper lip and a crease on my forehead. I also work full time and go to school, and I look tired all the time. Would love to look refresh at least, and if there are any miracles, of course look younger.

    Thank You

    Put me in the list for tester please!

  2. That’s 3-4 ttimes. And the “fast and amazing results” are about my facial appearance. Radiant and taut skin. I am 63 but look and feel 33 on DMAE. Truly an age-reversing nutrient in some respects.

  3. I use 100-200 mg every day or r-4 timrs a week. Fast and amazing results. Even moreso if I regularly use 250mg of DMAE daily. But I taper it as more than 100mg conistently interferes w/ good night’s sleep. DMAE has really sharpened my focus and memory and greatly lifts mood, well-being and sense of purpose.

  4. I am 43 years old and have suffered with rosacea for years. I also deliver mail for a living and I am diligent about spf on my skin. I would love to be a tester for preventive skin care.

  5. I just turned 69 and have always taken very good care of my skin and am very fortunate to have very few wrinkles…My mother is 101 and has very good skin… Over the years I have used some very expensive products, however,recently, I was divorced after 35 yrs and lost my job…So, I can no longer spend $500 for one jar of cream…I have done quite a bit of research on your products and am intrigued but with so many different products in your line I am confused as to what to buy…Since you are looking for people to test your products I would very much be interested in that…

  6. I tryed one of DR Perricones creams and i am hooked! I would love to try a cream that would take care of wrinkles and some sun damage. I heard Dr. Perricone’s new book is out. I will be 67 on my next birthday and want to look good as I age. I have a vegan diet but eat lots of salmon and green vegetables.

  7. Hi my kid has NCLS and we want to try DMAE to improve his condition, anny suggestion?

  8. I am a woman of color in my mid-40s and am not happy with the current condition of my skin – no vitality, not as firm as it use to be, uneven tone, and wrinkles in under eye area. I’ve just begun a weightloss regimine and would be thrilled to be a Perricone tester on my journey towards youth and beauty.

  9. Im 72 years old with lot of wrinkles would love to test this

  10. I am really excited to try your products. I am 40 and am worried about my crows feet and laugh lines. I really do not want to get a medical procedure and can not really afford it. testing perricone products would be a dream come true.

  11. I am 41 years old and would love to be a tester. My mother and grandmother have very wrinkly skin even though they eat healthy. I would love to prevent this from happening to me.

  12. I saw Dr. Perricone on the Dr. Oz show this week. He did a presentation on DMAE and I was very intrigued. I am 50 years old and have always been told that I look much younger. I am always trying new products and I am currently doing a few different things (microdermabrasion, laser, and a slight peel) at a laser clinic. I would love to be a tester for your products especially the DMAE.

  13. i am 43 years old, and my skin is not looking so fresh from all my sun abuse, my skin looks older than my 70 something mother, maybe around the same. sagging skin, wrinkles. i look young until you get up close and then, not so good. would love to test the products, i need help!

  14. HI I am interested in the DMAE solution for the face, and what do you recommend? I am 60 years old!
    Thank you, Sue

  15. I do use SPF 20 every day and moisturizing creams on a daily basis. But I have wrinkles around my eyes; my skin around mouth, cheeks and chin hangs more each year; I have a turkey neck. I’d love to be a tester. Thank you

  16. I would love to be a Perricone tester! I have been a professional swimmer and water polo player in college and have lots of fine lines. I would love to reverse or improve the damage I’ve done to my skin. I would like to see if this Perricone DMAE will help to improve my skin.

  17. I’m nearing the 40 yr mark and I’m starting to notice a big difference in my face. I would love to become a Perricone tester! I am looking for a way to turn back the clock that doesn’t involve going under the knife.

  18. I would love to be a tester, I have small lines above my lips and around my mouth.I am 68 years old.

  19. Which fish does DMAE come from? Does isolating the DMAE from the fish weaken its potency?

    I am interested in being a tester

  20. I have medium olive skin tone. I have deep wrinkles in my forehead, uneven skin tone, some whiteheads and some sun damage. I’m 56 years old, and haven’t always taken good care of my skin. Now, I’m trying. I could lose about ten pounds. Its scarry how quickly I’m aging, I don’t recognize myself. I looked into Dr. Perricone’s products after watching an episode of Dr. Oz where DMEA was introduced. I would like to be considered as a tester. Thank you.

  21. I would appreciate the chance to become a Perricone tester. I watched Dr. Perricone on the Dr. Oz show today. I am a 54 year old mother of three. We just got back from a family vacation and as much as I hate to admite it, I deleted the pictures that I was in with my children. I just hadn’t realized how old I was looking. It has made me want to change, inside and out!

  22. Just saw a Dr Oz show which recommended DMAE. I would love to try it to improve my skin, I had a terrible rash years ago which has stretched my skin around my neck, now at age 56 the wrinkle are coming on big time!

  23. I have wrinkles under and around my eyes, and around my mouth. I have tried numerous products that promise to reduce wrinkles, and not one of them has lived up to the claims made in the advertisements. My before and after photo’s would be an impressive testament to Dr. Perricone’s products.

  24. I would love to be a Perricone tester. I have never worn makeup. The extent of my beauty regimen involves a mild organic facial wash, lip balm, and a 45 SPF sunscreen. I work out daily, am an avid runner and practice yoga. My diet is primarily cold water fish, vegetables, fresh fruit, and whole grains. Perricone products seem like a perfect fit.

  25. I am 49 years old! I have very dry skin. I have to put lotion that my doctor prescribes to me daily or my skin gets flaky and wrinkly looking. I have fibromyalgia and just knowing that my skin is getting better would help with my depression which in turn helps with my pain. Please let me be a Perricone tester. Plus anything that might help my fibromyalgia symptoms I would love to test. If I could get my old life back I would be your biggest supporter.

  26. I turn 54 on 9-11 (great birthday, huh?). I would love to be a tester.

  27. I would love to become a Perricone tester. I was a sun worshiper in my younger days and am now beginning to pay the price. I am in my mid fifties and have lines above my lips and around my eyes and am beginning to sag.


  29. I just saw Dr. Perricone on the Dr. Oz show this morning and was interested in hearing about DMAE. As I was doing some research online, I came across this page. I am 45 years old, a teacher, a wife, and mom of 2 teenagers. I am very active, exercising at least 45 minutes a minimum of 5 days a week. I have noticed some lack of skin tone and have been moisturizing with a product that has an spf of 20. I would be very interested in becoming a tester for this product. I look forward to hearing from you. (sorry, realized I missed a letter in my e-mail address, resubmitted the whole comment).

  30. I just saw Dr. Perricone on the Dr. Oz show this morning and was interested in hearing about DMAE. As I was doing some research online, I came across this page. I am 45 years old, a teacher, a wife, and mom of 2 teenagers. I am very active, exercising at least 45 minutes a minimum of 5 days a week. I have noticed some lack of skin tone and have been moisturizing with a product that has an spf of 20. I would be very interested in becoming a tester for this product. I look forward to hearing from you.

  31. Just saw the remarkable effectis of DMEA on a woman while watching Dr. Oz. If I recall correctly, we are to find a topical product that contains DMAE. However, your website provides supplements. Even as a college professor, I’m a bit confused. At 62, and having spent many, many years involved in outdoor sports, I guess my wrinkles and lack of tone are expected.

  32. I am 58 years old and am active and fit. I just feel I need a little “boost”
    I would love to be a tester and see for myself that DMAE works!

  33. I am 69 years old and would like to feel better and
    fight wrinkles. Thanks, Georgia

  34. Age 54 going through peels. Deep laugh lines and wanting to avoid injections. Saw MD on Dr. Oz and am curious

  35. I would love to be a Perricone tester. I am 59 years old and have always taken care of my skin. I try to eat a healthy diet and stay out of the sun if I am not wearing sunscreen.

    I am noticing lines and sagging starting to happen!

  36. I watched Dr. Oz this a.m.. Dr. Perricone was a guest. I was amazed at the results of the before and after of the lady’s skin in the photo. I really want to use this product. I am always interested in helping the beauty of my skin. Thank you!

  37. Dr. Perricone is on Dr. Oz today – I admire them both! I would love to become a Perricone tester – pick me, please!

  38. Would love to be Perricone tester, the lines above my lips are very noticeable, even after I had restyline and I don’t smoke, I am dubious about getting more injections but if this product with DMAE really works??? I am 57 years of age and use SPF20 every day.

  39. I’m vegetarian and wanted to know if this product has any fish or animal biproducts in it? IF so, are there any vegetarian alternatives?

    Also , what is the best, vegetarian alternative to your Omega 3 supplement? That doesn’t have fish biproducts or gelatin?

  40. Since recently having a baby I’ve had small, puffy bags under my eyes and I just look tired all the time even when I’m well rested. I got the Made from Earth Vitamin Face Firmin Serum in the mail the other day and tried it…woke up this morning and I’m very impressed with the results! Just one use and I look well rested, refreshed and my skin looked visibly brighter! The bags are gone and my eyes look amazing!

  41. Greetings!
    I have always been out in the sun. Never used anything on my face so at 63 years old my eyes have bags under them. My face and neck have sun and wind damaged sagging skin and awful wrinkles. I would be quite a test subject for you. I thank you and wish you the best if you chose me. It would be quite a challenge to fix me!

  42. I am 53 and would LOVE TO BE A TESTER!!
    I try to be a very holistic type person, I am a nurse and in contact with many people everyday. I try to keep active and present a healthy image to all i come in contact with. Let me know what I can do to help.

  43. Dr. Perricone & Staff,
    I have purchased The Wrinkle Cure and Forever Young, as well as the 10 day diet supplements and a few trial bottles of facial line thru QVC.
    I am 52and want to become a Perricone Tester!
    Please consider me! Eileen

  44. If you need someone to test the DMAE I would be a perfect example of someone who has lots of skin damage from sun exposure and has to deal with basal cell skin problems. If your product could help me I know it would work wonders on others.
    I would be happy to try it out.


  46. I am going to be 54 in June and I have a 9 year old daughter. I am noticing sagging at the jaw line and would very much like to test your DMAE firming cream. I would like to restore my youthful appearance for my daughter’s benefit. I want her to feel comfortable being with me when I go to school functions, etc. and all the other mothers are so young.

  47. i am 47 and have never been one to do a lot of skin creams etc… but would love to try and test things thanks mary

  48. i am no beauty and could definitly use the brain boost

  49. I’m just going to throw caution to the wind and try one of the DMAE products. I’ve sent so much over the years and so far nothing is really working…so, what do I have to lose?

  50. I’m just over 40 and aging process has begun..I believe our bodies are our temple…treat it with kindness.So the best thing is to put good things into the body to help the aging process. Sometimes life doesnt treat us well and need a little extra help. I’d like to try this product. I like to look more awake and look I have the best sleep ever. Hey and if this products can help the sagging..I’m game!