Perricone MD – Cold Plasma

You’re an individual with unique skin care needs. Even if you and another person are both clinically healthy, one of you may need more of one type of nutrient than the other does. With this concept in mind, over the course of five years in collaboration with physicists at Los Alamos Laboratories, Dr. Perricone developed Cold Plasma, a revolutionary product to help enhance your current anti-aging routine through the power of biochemical individuality.

What is biochemical individuality, and how does this revolutionary product, Cold Plasma, work?

Learn more:

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Cold Plasma is a universal skin care product; suited for anyone, no matter how old your skin is, what your skin type is, or whether you’re male or female.

Cold Plasma works through a patented ionic (i.e. charged particles) suspension carrier system which allows for your skin to extract from Cold Plasma’s formula according to your individual, unique needs. This personalized system, called biochemical individuality, is a self-selection process charged by phospholipids, major cell membrane components. Phospholipids are fat derivatives which help lock in moisture, because phosopholipid bilayers have hydrophilic (attracted to water) heads facing outward and hydrophobic (mix poorly with water) tails facing inward toward each other. The phospholipids in this formula help direct needed nutrients where they can be effectively used through the cell membrane. This also means, if any of the ingredients aren’t needed, they just won’t be utilized.

Check out the latest Perricone sale for $10 samples!

Cold Plasma works through this system to deliver optimal nutrition to skin cells to help skin achieve a healthy, glowing, youthful appearance.

It does so by helping combat the 10 signs of aging, which include:

  1. Firmness
  2. Elasticity
  3. Clarity
  4. Radiance
  5. Smoothness
  6. Texture
  7. Redness
  8. Blotchiness
  9. Fine lines and wrinkles
  10. Dryness

Beyond the unique delivery system, the key sciences behind this product include:

  • Advanced neuropeptide technology to give anti-inflammatory effects, which assist in slowing the 10 aforementioned signs of aging.
  • DMAE to help stimulate nerve function, thus causing muscles under skin to tighten, providing a lifted and firm appearance to sagging skin.
  • L-tyrosine, an amino acid, brightens skin to help radiate a youthful glow.
  • DHA, an essential amino acid, to support the preservation and hydration of skin.

cold plasma

Cold Plasma contains no:

  • Parabens
  • Fragrance
  • Sulfates
  • Mineral oil
  • Artificial colors or fillers

According to Dr. Perricone’s recommendation, in the morning and evening:

  1. Cleanse skin, first
  2. Apply Cold Plasma
  3. Put on any Perricone MD treatment and/or moisturizer to finish

Can it get any better? – “I’ve been using Cold Plasma since its exclusive debut on QVC and have been amazed that my skin could actually look any better after five years on Perricone products. Yet it does! Brighter, firmer, smoother…all this and more…” —From

What a difference! – “Tone and texture has evened out, pores (which I was told mine were small, but were visible to the naked eye), are virtually diminished, I can only see them when I use the dreaded 10X mirror to pluck my eyebrows. The price is high, but the product goes very far, I am sold on the product, and will definately stay on the auto-delivery plan. I notice I am using less make up, so I figure the money will even out, in the long run. Its nice to get up in the morning and debate on even bothering with the make up…” —From QVC

Can’t live without it – “Great product, I highly recommend! I’m 40. I noticed a change in my skin tone, radiance and the big one– It softened my lines and wrinkles right away!!! This is a product I can’t live with out.” —From QVC

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857 Comments • Please comment below


  1. I have used perricone products in the past i really like your nutriceuticals line of vitamins, i would be interested in trying the cold plasma as i was doing a search on products good for large pores and this came up!

  2. Headr so much abouit this great products, I ordered today and can’t wait to get it so I can look yomger

  3. I love these products. I am using the cold plasma now, and want to get the cold plasma eye.

    I am 65, would love to be a tester. Thanks for offering such great products.

  4. I have tried and loved most of Dr Perricone’s products. The Cold Plasma sounds like he’s gone to a new level and would love to try it!!!

  5. Just purchased cold plasma and neuropeptide. I have been fortunate where my skin has held up well from an aging perspective (51). Over the past few weeks, I have seen more wrinkles on forhead. I am hopeful this product combination will improve that situation

  6. I would love to sample cold plasma….I just turned 60 and have noticed less firmness and more dryness and more winkles under eye area and on forehead.


  7. I’m getting ready to turn 48 and although I’m told that I look younger than my age, I’m truly starting to see more and more signs of aging — dark circles under my eyes, redness on the cheeks, and “worry lines” on the forehead. I have tried other high priced products but their effect seems to have diminished. I’d like to grow old “gracefully”. I’d love the opportunity to see if this product is as good as the reviews indicate.

  8. About to turn 58 and I look in the mirror and don’t feel as tired as I look. I see photos of myself and don’t recognize myself! And in the last year, dryness has set in. Sounds like these proudcts were designed to penetrate through the dryness. Whew . . . would love to test some of these products and report my successes

  9. i am 43 yrs old. I have lupus. I have always taken care of my skin since my teens..people have always told me i dont look my age at all. Since ive turned 40 i noticed my skin is always blotchy and red. Im starting to get laugh lines and my pores look huge to me. I would love to try this product to see if it helps. I normally use either Neutrogena or Shiseido products.

  10. I would love to try all of his products but cannot afford them. Not even on QVC.

  11. Cold Plasma: Great name! Plasma has the idea of blood infused or life-giving cream.

    I’m 69, look about 54, (I’m told over and over)would love to use your products, but hesitate to buy to get started, because of the price. I’m on a fixed income and wouldn’t want to love your product and them not be able to buy it. (Of course,I probably would if I knew it worked like no other in the market place.)

    So, I would love to try it for free and would enjoy giving a detailed review of how it worked on my skin.

    Looking forward to hear good news from you….


  12. I’m now 50, divorced and have to support myself, been back at school to try to get myself more employable but have been unsuccessful in gaining entrance to a medical radiology tech program – now trying to find a full time job to support myself after 18 years of being a full time mom.
    In the mean time, have some health issues and no health insurance, trying to keep a roof over my head and keep positive, my skin could sure use some help. Trying to compete with all these young people in this economy, I can use all the help I can get. I want my skin to look like I feel –

  13. I am 60 years old. I have surface dryness but still oily under. Lines, sagging skin and loss of firmness are my biggest problems. I really will love to try Cold Plasma and be a tester. Please help, thanks.

  14. I believe the anti-inflammatory properties of Dr. Perricone’s Cold Plasma is exactly what I need for my skin. Having been diagnosed with Type 2 Diabetes I’ve noted changes like drying, less skin elasticity and loss of that glow I use to have a couple of years ago. Some days the skin around my eyes seem puffy…especially under the eye. I’m also menopausal and have wondered if hormone changes might also be causing many of these changes I’m experiencing. I’ve never been a heavy makeup user so I know that I haven’t abused my skin with synthetic products and I haven’t spent too much time in the sun either. Perhaps Dr. Perricone’s product can make the difference…I’m willing to try it.

  15. I love your products and would love to try your cold plasma. After reading all these comments I think this would be the icing on the cake for my skin. Can’t wait to hear that I won. :)

  16. I love this product! It works instantly. I trust no one but Dr. Perricone when it comes to my skin! I get compliments all the time. I am 30 and everyone thinks I am in my mid 20s. Yay! Thanks~~!

  17. I am now 51, a single mom, and have struggled with adult acne, psoriasis, and eczema for years…I am also seeing more “not-so-fine” lines!! I would love to win, love to be a tester, would love to be able to tell all my friends and family that this works! Please help :)

  18. Every product i have tried on my face does nothing for the redness i have to deal with on a daily basis,its so embarrising.
    Every since i samples Perricone products i been a fan!

  19. My skin is losing elasticity and new little lines appear every day.I would never submit to an actual surgical produre to inprove my skin but would love to try this as a noninvasive alternative.

  20. Reading about Cold Plasma and regarding my age (51) this product also can be part of my total package and this way have the best result with the full line of our products. Great oportunity for be a tester in full.

  21. I need to try Cold Plasma in order to treat
    my 10 signs of aging.

  22. I’ve heard nothing but wonderful reviews of this product. I just turned 50 and even though my skin is okay, I want it to be RADIANT!! I want, no wait, I need younger looking skin. I would absolutely love to try the Cold Plasma. It sounds perfect!

  23. I’m going to be 50 this year. I’m Japanese and always thought I would have flawless skin. How wrong was I?? Now I have dark cirles under my eyes, brown spots on my cheeks, and oh no, I’m even getting some wrinkles! Help!!

  24. I have super dry skin and could use some help!!

  25. [...] like Oprah.  After 5 years of intensive research guided by a lifetime of scientific insight  Cold Plasma Dr. Perricone was [...]

  26. My skin is in horrible shape with this harsh winter. I need to restore it. It seems your cream can do just that.

  27. I’ve just purchased cold plasma and I’m wondering if I can use it on my eyelids and under my eyes, along with the rest of my skin.

  28. I am getting wrinkles and could really use this.

  29. This cream sounds fabulous. I am seeing more lines and wrinkles everyday. My skin type has also changed to dry. I would love to handle all my skin issues with one cream.

  30. I am 60 years old and have had surgery on my upper lip to remove deep basal cells about 10 years ago. The surgeon told me I would have a permanent pull on my lip. It didn’t bother me that much but as I age it is becoming a deep crease which makes feel self conscious. I would love to try the Cold Plasma to see if it would help soften the line. I would love to put Dr. Perricone’s products to the test. If I’m happy I would be a strong advocate of his skin care products. Please consider giving me this wonderful opportunity

  31. I am constantly looking for skin treaments. I am 70 years old and would like to preserve my skin and still look youthful.

  32. Thirteen years ago, I quit drinking alcohol and started going to the gym; five years ago I quit smoking cigarettes and started hydrating, but unfortunately, the combination of the above with the many years of working (albeit carefree and happy) in all weather conditions has left my skin telling the signs of a life well-lived without concession for proper sun protection.

    I know I can not turn back the clock and I appreciate the “happiness lines” around my eyes (but could do without the faint lines on my forehead or upper lip). Although I am trying to catch up with good skin care practices, I have troubles keeping track of complex skin care regimes, and was attracted to Cold Plasma’s “all in one” promise.

    Dr. Perricone’s product looks like a skin care solution that would work for me but, at this time in my life, it is way outside of my budget. I of course would be utterly delighted to test the product, because when I finally get my book deal, skin care will be one of the first things followed through on my wish list.

  33. After several years of trying every acne remedy in the book; proactiv, retinol creams,and harsh microdermabrasion treatments, my skin has yet to transform itself. I’m only 21 and I feel like I look at least 30 because of all the stress that my acne problems give me. I no longer have cystic bumps, but I do have deep blackheads embedded in my skin. I would love to use Cold Plasma; it sounds promising.

  34. I have been given fabulous DNA: great facial structure and skin. I was taught early to stay out of the sun, hydrate, clean and moisturize. I doubt you could guess my age. If you went on Facebook and looked for Linda Shields, you would see my face. I would make an excellent tester: 1)I am a scientist, used to conducting experiments 2) My face truly matters to my self-esteem 3) I follow instructions all the way 4) I document well 5) I am tech literate. Thank you for your time and attention. Linda

  35. This product looks like it would work wonders on my dry skin. I also think it’s fantastic that it doesn’t use parabens or fragrances.

  36. Cold Plasma is the Best. I am impressed with Perricone’s products. They work.

  37. OMG. I am sooooo amazed with Perricone products as they truly make a difference in reducing aging. I have learned alot about their products having met Perricone reps through Nordstrom. Highly recommend his products.

  38. Oh, I’ve been coveting this product for a while! As a redhead, I’m always on the look out for a face cream that’s effective AND gentle. I suppose I should mention that I’m not getting any younger, either!

  39. At age 38 I had to have a total hysterectomy. I was put on hormone therapy right after which in turn was harsh on my skin. I have brown patches on my face and my skin is extremely dry. I used to have a peaches and cream complexion. Now after 6 different surgeries and all of the medication I am taking it is wreaking havoc on my skin. I will be 50 this month and I just want to look good for my age. I would absolutely love to try Dr. Perricone’s cold plasma and see if it can help me to feel better about myself.

  40. At age 38 I had to have a total hysterectomy. I was put on hormone therapy right after which in turn was harsh on my skin. I have brown patches on my face and my skin is extremely dry. I used to have a peaches and cream complexion. Now after 6 different surgeries and all of the medication I am taking it is wreaking havoc on my skin. I will be 50 this month and I just want to look good for my age. I would absolutely love to try Dr. Perricone’s cold plasma and see is can help me to feel better about myself.

  41. This sounds like something I need for my dry,aging cheeks this winter. I haven’t heard of this product before, it sounds wonderful!

  42. At 56, I really could use some help with discolorations which are noticeable now and sagging/flabby skin on my face. I followed Dr. Perricone’s eating plan and it made such a difference, that I feel confident in him and that his Cold Plasma will work for me.

  43. I’ve been looking for a product that will prevent aging. This product sounds amazing, will definitely be saving up for this one!!

  44. As an African-American women, you always here stereotypes on how we do not get wrinkles (we do). As I was informed, there’s little about African-American skin that is safely assumed, except that it can be supersensitive. My skin will rebel against the wrong products by developing a discoloration that can stick around for months or years. I been able to change this with Perricone products and would love more.

  45. I am a 33 year old recently diagnosed with a rare skin disease. After struggling for over a year with prescription creams, drugstore creams and everything in between, I have found my miracle in Cold Plasma. I am regaining the skin I used to have and my confidence along with it. Thank you Dr. Perricone!

  46. I’d love to try this new product. I’m 62 and have been using Perricone products and the supplements daily for a number of years. I’ve been satisfied with the results so feel certain that this will probably live up to it’s name. Thank you

  47. I could really use some help with the redness & blotchiness on my cheeks as well as with overall dry skin.

    Travel to New England on a regular basis in the winter wreaks havoc on my skin.

  48. I have sensitive skin and am turning forty this year. I need to find a new product to help my skin look younger since I now have all ten of the “10 signs of aging” the product is said to address. I have used another brand/product line for years but find even their “best” is not doing the job now so i am ready to move on. I received a free sample of another Perricone MD product that I absolutely loved, so I hope I will love this one too —and I sure hope I win some!!!

  49. Great product for my very dry skin. Thanks so much!!

  50. I’ve heard wonderful things about this product and would love to try it! I’ve suffered from adult acne and eczema and I’d love to find a product that helps with the resulting blotchiness!

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