Perricone MD – Cold Plasma

You’re an individual with unique skin care needs. Even if you and another person are both clinically healthy, one of you may need more of one type of nutrient than the other does. With this concept in mind, over the course of five years in collaboration with physicists at Los Alamos Laboratories, Dr. Perricone developed Cold Plasma, a revolutionary product to help enhance your current anti-aging routine through the power of biochemical individuality.

What is biochemical individuality, and how does this revolutionary product, Cold Plasma, work?

Learn more:

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Cold Plasma is a universal skin care product; suited for anyone, no matter how old your skin is, what your skin type is, or whether you’re male or female.

Cold Plasma works through a patented ionic (i.e. charged particles) suspension carrier system which allows for your skin to extract from Cold Plasma’s formula according to your individual, unique needs. This personalized system, called biochemical individuality, is a self-selection process charged by phospholipids, major cell membrane components. Phospholipids are fat derivatives which help lock in moisture, because phosopholipid bilayers have hydrophilic (attracted to water) heads facing outward and hydrophobic (mix poorly with water) tails facing inward toward each other. The phospholipids in this formula help direct needed nutrients where they can be effectively used through the cell membrane. This also means, if any of the ingredients aren’t needed, they just won’t be utilized.

Check out the latest Perricone sale for $10 samples!

Cold Plasma works through this system to deliver optimal nutrition to skin cells to help skin achieve a healthy, glowing, youthful appearance.

It does so by helping combat the 10 signs of aging, which include:

  1. Firmness
  2. Elasticity
  3. Clarity
  4. Radiance
  5. Smoothness
  6. Texture
  7. Redness
  8. Blotchiness
  9. Fine lines and wrinkles
  10. Dryness

Beyond the unique delivery system, the key sciences behind this product include:

  • Advanced neuropeptide technology to give anti-inflammatory effects, which assist in slowing the 10 aforementioned signs of aging.
  • DMAE to help stimulate nerve function, thus causing muscles under skin to tighten, providing a lifted and firm appearance to sagging skin.
  • L-tyrosine, an amino acid, brightens skin to help radiate a youthful glow.
  • DHA, an essential amino acid, to support the preservation and hydration of skin.

cold plasma

Cold Plasma contains no:

  • Parabens
  • Fragrance
  • Sulfates
  • Mineral oil
  • Artificial colors or fillers

According to Dr. Perricone’s recommendation, in the morning and evening:

  1. Cleanse skin, first
  2. Apply Cold Plasma
  3. Put on any Perricone MD treatment and/or moisturizer to finish

Can it get any better? – “I’ve been using Cold Plasma since its exclusive debut on QVC and have been amazed that my skin could actually look any better after five years on Perricone products. Yet it does! Brighter, firmer, smoother…all this and more…” —From

What a difference! – “Tone and texture has evened out, pores (which I was told mine were small, but were visible to the naked eye), are virtually diminished, I can only see them when I use the dreaded 10X mirror to pluck my eyebrows. The price is high, but the product goes very far, I am sold on the product, and will definately stay on the auto-delivery plan. I notice I am using less make up, so I figure the money will even out, in the long run. Its nice to get up in the morning and debate on even bothering with the make up…” —From QVC

Can’t live without it – “Great product, I highly recommend! I’m 40. I noticed a change in my skin tone, radiance and the big one– It softened my lines and wrinkles right away!!! This is a product I can’t live with out.” —From QVC

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857 Comments • Please comment below


  1. Does anyone know whether this product is okay to use with sensitive skin? How about in conjunction with a retinol?

  2. I will be turning 40 next year and just starting to develop fine lines and my skin doesn’t like as radiant as it used to. This sounds like the product I have been looking for as it sounds like it could solve the problems I am developing. But I can’t afford to try it unless I know it truly works as I am a single mom to 5 kids. But if I were to win a sample and find it works, I would become its biggest advocate!

  3. I am almost 40 so u know that is when everything starts to change. I have had a hard time with any product I have used. It would be great to be a tester for your product. I am very excited to try it.

  4. perricone is the best skin care ever.
    These are products that perform as they say, no question. It is worth the money.

  5. I am in my thirties, and even though i live a healthy lifestyle (using spf, drinking lots of water, and using non toxic makeup) i have noticed some of those dreaded ‘aging signs’ begin to make their way onto my skin. I have never tried a perricone product before although i have seen the line multiple times. This new product seems like it would benefit me in that i am showing nine out of the ten signs that the product addresses. How wonderful to find a product that can address so many things at once!! Therefore i may be able to only use ONE product (perricone) instead of multiple products that i am currently using!! Thank you for considering me!! :)

  6. i’ve always tried a hodge-podge of products but have read about perricone for a long time and would love to see if there really is a difference in these products. i tend to try and do some research before i purchase.

  7. I am thirty five years old and notice alot of happy lines appearing,thought it was to early to notice,but they crept up on me!I am very concerned and would love to try your product!

  8. I’m over 40 and have noticed a major change in my skin lately. My old skincare regimine just doesnt seem to be working. I’d like to try this to see if it could help me.

  9. Sounds like what I need! Enter me to win!

  10. I would be a perfect tester. I have all the signs of aging that this product addresses! I would love to have healthy, less aged-looking skin!

  11. Life can be difficult–a parent of a permanently disabled son, a spouse of an ill husband, and an unsupportive boss–and it can all be seen in the face. Try as I may to take care of myself, sometimes life just is what it is. I have tried Perrisone products and love them (especially the restorative night cream), however, money is short so what I can buy is limited. You ought to let me be a tester, I have a face that could use some lifting (along with spirits!).

  12. I am 56 and have delevoped a red rash on my face that the doctor said would be something I will combat for the rest of my life. I have been very depressed about this due to my having had very pretty skin. I was reading a magazine this morning and read about Dr. Perricone’s Cold Plasma and am hoping this might just be the product to start revitalizing my skin and stimulate new healthy skin growth. Thank You! I’d Love to test it!

  13. I am 55 years and seven months old, but my 15-year-old daughter’s friends say they think I am 36, and that I’m joking about being nearly 56! In the past, I have used La Mer, Sisley, Arbonne, et al., but Perricone takes the cake (hands down!). Especially during a year when I have had four major surgeries (breast cancer-related) with anesthesia and pain killers often in my system — as well as, at times, zero immune system — it is nothing short of miraculous that my skin is still glowing. I have just ordered first jar of Cold Plasma, so cannot comment yet on that particular product, but every other product I’m using is a 20 out of 10, as it were! My orders keep getting bigger, as I am committing at last to supplements and anti-oxidant diet, which are also tantamount to keeping creepy cooties from taking over my body!

  14. This sounds like such a great product. I have been having all sorts of skin issues for awhile now and am trying to find something that really works. I would love to try it!

  15. [...] Perricone Cold Plasma is an anti-ageing breakthrough which resulted from five whole years of scientific study. When we announced in last week’s fashion newsletter that we had not one but five Cold Plasma gifts – valued at $150.00 each – to give away, the interest was so strong we thought it would be unfair not to give everyone a chance. [...]

  16. I am 38 years old and still get cycles of severe acne. I love Dr. Perricone’s books because he backs up what he says or sells with the science to prove it. I would love to test cold plasma. I would go out and buy Dr. Perricone’s whole skin care line if I wasn’t a graduate student in college. But the advice in his books is clear and works! I have confidence that this product works as well if Dr. Perricone says it does. I would love to test it not only for its advertised benefits, but to also see if it would have a positive effect on my adult acne as well. Thank you!

  17. I have used Perricone products before. Love fragrance free! I would love to receive a sample to test the product. I might actually splurge on it if I really like it.
    Send me some, please……

  18. I am 60 years old, and am looking every year of that. My neck is showing lines and riplled look, my jowls are starting to droop and my eyes appear to be tired looking. Please help me.

  19. [...] Perricone Cold Plasma is an anti-ageing breakthrough which resulted from five whole years of scientific study. When we announced in last week’s fashion newsletter that we had not one but five Cold Plasma gifts – valued at $150.00 each – to give away, the interest was so strong we thought it would be unfair not to give everyone a chance. [...]

  20. [...] Perricone Cold Plasma is an anti-ageing breakthrough which resulted from five whole years of scientific study. When we announced in last week’s fashion newsletter that we had not one but five Cold Plasma gifts – valued at 0.00 each – to give away, the interest was so strong we thought it would be unfair not to give everyone a chance. [...]

  21. I have tested many different product lines and am most happy with the Skin Ceutical line and all of the research done in the development of each product. I’m 57 and have an identical twin. . .she does not ‘invest’ in quality creams and serums and there is a noticeable difference our facial aging process. I have not yet tried the Cold Plasma, but look forward to the opportunity!

  22. I’ve been using Dr. Perricone’s products for years, and have been a very satisfied customer, who is frequently mistaken for a much younger woman. But something seems to have changed, and I feel I need either some new advice about which products to use, or some new products themselves. Certainly, the Cold Plasma sounds great, and I would be very happy were I to be chosen as a tester.

  23. I saw an advertisement for this product in a magazine. I wish one product could really do it all – and i would love to put this one to the test!

  24. I am 55 and would love to test the new Cold Plasma product. I have read Dr. Perricone’s books and what draws me to his products are the science behind the products. I have loved the Perricone products that I’ve tried so far.

  25. I would love to become a Perricone tester. I am 44 years young and looking for products to help me stay youthful. I think Perricone products, supplements, and nutrition advice could help me achieve this goal. Also,
    I am the go to person for fashion and cosmetic advice with my friends.

    I would be truly honored to be a Perriocone tester. Please pick me!

  26. It looks amazing! As 40 stares my in the face – literally – need something to fight the anti-aging process that will give my skin exactly what it needs. Not some generic trying to be sophisticated. I have all 10 signs on the anti-aging list – to varying degress of course. Also love this product contains none of that other nasty stuff, like parabens, that overly marketed products do. For someone trying to go more organic and natural like me this is perfect. My friends always ask my advice for facial products since I infrequently wear make-up but always try new products. Always thrilled to test and provide honest feedback and spread the word of effective products.
    tvollowitz at aol dot com

  27. I’d love the chance to be a Perricone tester!
    I’m 56 yrs old, my skin is beginning to give my age away. I am beginning to see forhead wrinkles and my eyes make me look tired from the dark circles.
    I am a normal skin type not to dry or oily. I treat my skin with over the counter products.
    Hope you choose me!!


  29. I recently got the Perricone No Foundation Foundation and I love it. Cold Plasma sounds every bit as amazing!

  30. Wow, Cold Plasma sound amazing, I like that it gives my skin the correct amount of nutrients it needs, as if it was made just for my skin!

  31. I am a huge Perricone fan, and like so many people right now, I’m on a tight budget. I would love the chance to test anything in the Perricone line!

  32. I have 9 of the 10 problems that this product is supposed to help. I would love to fix all those. Thanks!

  33. I am 65 years old and a retired school teacher. I like to try every thing that has to do with looking better, especially items to help my skin. When it comes to cosmetic products, hair products, etc., my friends all ask me what the best products are. They know I keep current. I am changing my web site to include a blog to inform the public about a lot of issues I am interested in. The best anti-aging products are on the top of the list.
    Being retired, the prospect of testing products is a dream come true. I hope you will select me.

  34. I’ve used Perricone products in the past but the Cold Plasma addresses all the areas I need help with in one formula. Too good to be true. I’d love to be a tester for this one!

  35. I would love to try this product. I turn fifty this month (so hard to believe!) and I am beginning to see fine lines and wrinkles. It would be great to combat these changes for as long as possible. Everything I have read has rave reviews about the Perricone products.

  36. [...] Perricone’s Cold Plasma is a topical cream that addresses a number of skin problems. This can be helpful for people with [...]

  37. I would like to be one of your testers. I have sensitive skin with rosacea pretty well controlled with Metrogel and Replenix products. I am looking for anti-aging products that will work on sensitive skin. I have used the Perricone lip plumperin the past and was not happy with it. Was wondering if there is a lip plumper that really works.

  38. [...] you want Perricone Cold Plasma for [...]

  39. Perricone products have been excellent for my skin. I am reading everything I can find to take care of my skin which is lined but getting better. I would love to be a tester for Cold Plasma.

  40. November 5th will be my 67th birthday, and I’m not celebrating my skin tone and large pores these days! My face would be a real test for these products and it would be a joy to test any or all of them. The face shows the joy of the soul.Cheers!

  41. I have been using Dr, Perricone’s products now for three years and people have asked me what have I done to my face! I am 62 and people think I am 50. I am interested in the cold plasma that seems to be everywhere. But I am a little hesitant that one product can take care of what a number of Perricone’s do. So I would like to become a believer!

  42. I’m 63 years old and have been using Perricone products since they came on the market. During the past six months I have sadly watched my forehead become home to horizontal lines, my cheeks sag and now have vertical lines on them and the skin on my neck lose its elasticity. It is frustrating and depressing to see this happening and feel helpless to control it. I am looking for something that’s free of harmful ingredients like parabens and that actually works. I have faith in Perricone products, particularly the eye cream and the concentrated restorative cream, but now I think I need something more. I would love to be a “tester” for what sounds like an exciting new Perricone product. Thank you!

    Congrats! This comment has been chosen as our first winner for Cold Plasma!

  43. I use Euoko products. I would like to see how Dr. Perricone’s products compare.

  44. On my twitter acct, I follow The Lovely Luxe Tips, and lo & behold, she mentions my fave all time skin Doc of the world, Perrcone! Now he has a new product out! My sensory tingles like Spidey Man! I have tried the DMAE, the peptides, the pheromones, and It keeps me lovely at 48 yrs! I like how Dr. never revels his age, he just lets you keep guessing by his own product use to his own being! He sure does look good. And I sure want to keep looking good like that too.His stuff really, really works!! He puts heart, soul, intellect, knowledge, life works into his work. Hats off to the P-Man, and I hope I win babies!

  45. I have watched Dr. Perricone’s KPBS specials and have been dying to try his products. I am in my late 30-s, a pretty critical age and a delicate stage for skin, and my skin needs help! I would be happy to test Dr. Perricone’s products and report back.

  46. I am very interested in skin care and want to look as good as possible. I would rather do this with products if possible, rather than having injections or even surgery

    I am 62 and what bothers me are the lines around my lips and the lack of firmness around my jaw area. I am also beginning to get lines in the forehead area. My hands have brown spots and I am very ashamed of their appearance.

    Two weeks ago I started using your high potency eye cream treatment. I really do like this product and would really like to be one of your testers.

  47. this sounds like a fabulous product that contains no junk which would help my sensitive skin along with the redness and fine lines that I experience — thank you!

  48. Cold Plasma is the real deal. I thought that Perricone products were wonderful before. The new Cold Plasma takes skin care to a new level. And the Cold Plasma club kit is a terrific value. Not to mention that the included Serum Prep no longer smells like fish! LOL.

  49. [...] years of intensive research guided by a lifetime of scientific insight has yielded Cold Plasma, a breakthrough in skincare technology from renowned healthy aging expert Dr. Nicholas [...]

  50. I have been using Dr. Perricone’s basic products successfully for nearly two years. It excites me to think there are newer better products he is introducing, but I am anxious about spending a lot of money in case the new product does not work for me. That is why I would like to test Cold Plasma. I believe fully in Dr. Perricone’s approach to healthier living. Thank you for your research, Dr. Perricone.