Perricone MD – Cold Plasma

You’re an individual with unique skin care needs. Even if you and another person are both clinically healthy, one of you may need more of one type of nutrient than the other does. With this concept in mind, over the course of five years in collaboration with physicists at Los Alamos Laboratories, Dr. Perricone developed Cold Plasma, a revolutionary product to help enhance your current anti-aging routine through the power of biochemical individuality.

What is biochemical individuality, and how does this revolutionary product, Cold Plasma, work?

Learn more:

Try Perricone for as little at $10.

Cold Plasma is a universal skin care product; suited for anyone, no matter how old your skin is, what your skin type is, or whether you’re male or female.

Cold Plasma works through a patented ionic (i.e. charged particles) suspension carrier system which allows for your skin to extract from Cold Plasma’s formula according to your individual, unique needs. This personalized system, called biochemical individuality, is a self-selection process charged by phospholipids, major cell membrane components. Phospholipids are fat derivatives which help lock in moisture, because phosopholipid bilayers have hydrophilic (attracted to water) heads facing outward and hydrophobic (mix poorly with water) tails facing inward toward each other. The phospholipids in this formula help direct needed nutrients where they can be effectively used through the cell membrane. This also means, if any of the ingredients aren’t needed, they just won’t be utilized.

Check out the latest Perricone sale for $10 samples!

Cold Plasma works through this system to deliver optimal nutrition to skin cells to help skin achieve a healthy, glowing, youthful appearance.

It does so by helping combat the 10 signs of aging, which include:

  1. Firmness
  2. Elasticity
  3. Clarity
  4. Radiance
  5. Smoothness
  6. Texture
  7. Redness
  8. Blotchiness
  9. Fine lines and wrinkles
  10. Dryness

Beyond the unique delivery system, the key sciences behind this product include:

  • Advanced neuropeptide technology to give anti-inflammatory effects, which assist in slowing the 10 aforementioned signs of aging.
  • DMAE to help stimulate nerve function, thus causing muscles under skin to tighten, providing a lifted and firm appearance to sagging skin.
  • L-tyrosine, an amino acid, brightens skin to help radiate a youthful glow.
  • DHA, an essential amino acid, to support the preservation and hydration of skin.

cold plasma

Cold Plasma contains no:

  • Parabens
  • Fragrance
  • Sulfates
  • Mineral oil
  • Artificial colors or fillers

According to Dr. Perricone’s recommendation, in the morning and evening:

  1. Cleanse skin, first
  2. Apply Cold Plasma
  3. Put on any Perricone MD treatment and/or moisturizer to finish

Can it get any better? – “I’ve been using Cold Plasma since its exclusive debut on QVC and have been amazed that my skin could actually look any better after five years on Perricone products. Yet it does! Brighter, firmer, smoother…all this and more…” —From

What a difference! – “Tone and texture has evened out, pores (which I was told mine were small, but were visible to the naked eye), are virtually diminished, I can only see them when I use the dreaded 10X mirror to pluck my eyebrows. The price is high, but the product goes very far, I am sold on the product, and will definately stay on the auto-delivery plan. I notice I am using less make up, so I figure the money will even out, in the long run. Its nice to get up in the morning and debate on even bothering with the make up…” —From QVC

Can’t live without it – “Great product, I highly recommend! I’m 40. I noticed a change in my skin tone, radiance and the big one– It softened my lines and wrinkles right away!!! This is a product I can’t live with out.” —From QVC

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857 Comments • Please comment below


  1. I was very doubtful that this was real. But I love it and all of the doctor’s products.

  2. I want to win this jar of Sub D. I had bariatric surgery three years ago. Although I lost weight and improved my health, my facial appearance suffered. Being heavy in the face is youthful looking, losing the weight just made me look old. My skin sags at the jawline and I am anxious to see if Dr. Perricone’s Sub D can help me. Thanks for offering the opportunity to win your product.

  3. I’ve heard great things and would love to try cold fusion before I buy. Is there any way to get a sample?

  4. I would like to compare Dr Perricone’s new treatment and if given the opportunity that it works I would be willing to blog for him and be a loyal customer .

  5. I absolutely love Cold Plasma and it is the only thing that makes my skin glow. I hate to be without it!

  6. I have been trying all of the drug store brands for years, and somehow I have just become my mother. It must be hereditary. I would love to try Periricones formula before committing to it as money is a big factor.

  7. As I age, I’m seeing more lines, creases and wrinkles :( I’ve tried some of Dr. Pericone’s other products and love them. I think I’m ready for the Plasma Cold D.

  8. Have been using Cold Plasma for almost a year now & I’m very happy with its result. My skin became smoother, firmer * resilient. I’m happy to recommend it to improve your skin texture.

  9. [...] A big “Thank You” goes out to all of you that took the time to enter this giveaway for a jar of Perricone Cold Plasma. [...]

  10. Just received my first Sub D and cold plasma. It feels wonderful, I can see and feel changes with the first use.

    Try this product…its Fantastic!!! I am 61 year old.

  11. Can I use cold plasma and face moisturizer and Vitamin c Ester only instead of a hundred things on my face.

  12. I would like to see a change in my skin everything that i have tried has not worked i have had discoloration to my neck for the past five years and not even doctors have been able to help with it i’am so ashamed to wear low neck clothes because of it i wish so much that i could find a product that can help i would like to know if the cold plasma will help my neck

  13. I have had major neck surgery which has caused sagging in my neck area and I would love to see if this would help tighten my skin.

  14. Hi. I have always struggled with my skin starting in 4th or 5th grade. I am now 40. Still struggling. I don’t have severe acne and my enemy is myself. I spend hours examining my skin my face and see all the imperfections. The holes called pores. I would say that the last 1-2 years they have just gotten A LOT bigger. I just can’t comprehend that there isn’t a solution. The saddest part is that I am “considered beautiful” by reasonable people…I just see an ugly face most of the time with holes in it. I just want help. The reviews for the cold plasma give me some hope. I just want to get my pores tighter and see the beauty others see in me. I just want to love myself and as superficial as it is and vain, I can’t love the face that stares back at me. Should I give this product a chance? Sadly, I am actually a licensed esthetician that can’t figure out what is best for my own skin. I would love feedback and direction. Lol…I already have a therapist! :)

  15. would like to see if it really works

  16. Fixes every flare-up: When my skin becomes red, or shows the least irritation, I reach for Cold Plasma and it soothes and corrects any skin problems I have.
    It is the one “go-to product” that I can count on to keep my skin healthy and glowing. It really is everything that it claims to be.
    I’m on auto-ship for Cold Plasma, as it is the one Perricone product that my skin craves, and I don’t want to be without it. It really does everything that Dr.Perricone says it does!

  17. I have just turned 69 but feel like I am in my 30′s. I had acne as a teen and early 20′s. I have some scarring and large pores. I am showing signs of sun exposure, wrinkles, sagging, dull skin.

    Is there any hope for improvement. I try all sorts of products and try to eat healthy and exercise. I just don’t know if I am wasting my money on products that will never work. Is is too late for me? I would appreciate any advice you could offer me. Thank you.

  18. Hello! I am a 46 year old hispanic woman from Texas, and I have been wanting for so long to give the Perricone MD products a try for some time now. I recently went through my cabinets feeling quite disgusted at the cost and time wasted at the sight of countless jars, bottles and tubes of less expensive products that promised a real difference, and failed miserably.
    My combination skin with noticeable pores has some redness and prone to occasional breakout. I’ve noticed increasing lines around my eyes and I have convinced myself that smiling less will help!

    I would love to try Perricone MD!

    To quote a line from the movie Steel Magnolias: Truvy: Honey, time marches on and eventually you realize it is marchin’ across your face!

    Many Thanks!!

  19. I have been diagnosed with acne rosacea which i thought was under control. I wash my face daily with Cetaphil and Prascion cleansers and use Metrolgel at night. However, right now i am suffering from a flare-up that i think is due eating very hot salsa three days ago. My forehead and cheeks are all red and have raised bump-type blemishes. I need something to calm and sooth my face. I look just terrible! Make-up can cover the red but my face is so bumpy it can’t be hidden. Please send me some samples of your product so i can try and see if this is the answer I’ve been searching for. Thank you.

  20. Fabulous 50′s have come and are gone with my birthday this year. I have had oily skin all my life so learning how to work with drying menopausal skin has been a learning experience. I have tried numerous product to help reduce the age spots and restore some of my skins resiliency. Finding suitable products for post-menopausal women SHOULD be a focus … and even more so, they SHOULD help. Letting women believe they have to age with little or no recourse other than blind acceptance seems a bit out of place with all the advances in skin care and science. Hoping that these products can make a small difference… I don’t want to be 20 again… just a fabulous 60… without surgery.

  21. I ave Dr. Perricone’s book and ave always wanted to use his products. Since they are an investment I would live te opportunity to test them and see what works. Unfortunately, I have rosacea so my skin s a constant challenge.

  22. I don’t even look in the mirror anymore,looking for a product that can help sagging old looks like this cream may help.

  23. First Thank You Dr. Perricone!! I injurd my back two years ago. Your anti-inflammation diet saved me from surgery and keeps me active in life and work. I have a four year old son that keeps me very busy. We were fortunate to have him through invitro. Between the invitro and working part-time as a nurse so I can be with him as much as possible, my funds for beauty products are limited.
    My skin is starting to show my age. I have melasma from sun and fertility medications. I have wrinkles galore. But the worst is my sagging face. It seems to have become worse more recently. Please help me feel and look healthy. I hope I am picked. It would make the world of difference in my life!!

  24. I just tried a sample of the cold plasma and I swear I saw immediate results! I’m 37 and have dull, sun damaged skin and would love to be a tester! After many years of being on pain meds and many hospital stays, my skin could definitely use some help.

  25. after using dr. obagi zo product – my skin is so dry and irritated—it feels terrible–i would love to see if cold plasma helps!

  26. Im 65 and am in good health bu, my neck shows my age. I’ve tried many products nothing seems to help. Please help!

  27. November is my birthday month – the 25th to be exact and I will be 59. Yikes – don’t know how that happened. Other than the fact that this would be a great birthday present – I have thought about using Dr. Perricone’s products for years. I have always heard great things about them. My age/sun spots and wrinkles have become much worse in the last few years. I would love to try any samples, be a tester or win any of Dr. Perricone’s products that would be suitable for my age group. Please help me before it is too late. Thank you so much and Happy Birthday to me (hopefully from Dr. Perricone) lol

  28. I have just turned 40 and have noticed a major change in my skin. It is saggy and dull. I also have essential tremors. They have gotten much worse lately and I am trying very hard to not have to resort to medication. I am going to try the 3 day diet and see if I notice a difference in either (a change in both would be great). Some people with essential tremors find relief in following a mediteranean diet-which this is.

    I would love to be a tester! Anything would be great :)

  29. I received a small sample of Cold Plasma and am very excited! I don’t know if it is just my imagination- but my skin seemed less red already! I would live to test other Perricone products!

  30. I would LOVE to test any products Dr. Perricone has to offer. I am 36 and have melasma from my last pregnancy two years ago. I also have broken capillaries and dark spots from acne. Please help me!! Thank You!!

  31. :)

  32. im looking for a product that really works.

  33. I try products off and on but haven’t gotten into a daily beauty regiment. I’m looking for something that will tighten the skin on my neck along with collagen building in my hollowed out face. If you have products that would help these areas I would love to try any old or new products developed for these problem areas.

  34. I like to know if is tested on animals?

  35. [...] wanted to share my opinion about one product – Perricone Cold Plasma.  I was fortunate enough to win a jar of this and was really intrigued about its effectiveness.  [...]

  36. I am 39 years old, and for the past 20 years, I have used Clinique. People have always complimented me on my complexion and youthful appearance, but lately, my skin has changed. I never had acne, as a teen, and lately, I started having blemishes quite frequently. My skin went from dry to combination. I begin noticing little rosacea-like spots. One day, while visiting a friend, she offered me a small container of the Face Finishing Moisturizer. I took it home, started using it, and almost immediately, I noticed positive results! In fact, my husband who never notices things like that actually complimented me on my skin. I informed him that I had tried a sample of Perricone MD and that I loved it, and he told me to buy more! I’ve now used it for two months, and I am so pleased with my new skin! I would love to test the other products Perricone MD has to offer.

  37. Love the cold plasma amd would love the opportunity to test more producta..

  38. I’ve been a devoted Perricone fan since 2006. In fact, I was one of the
    three fortunate 1st place winners of the “Bikini Boot-Camp” Fresh Start
    contest! I have fibromyalgia & I began to feel so much better being on the anti-inflammatory diet, taking the supplements & beginning to excercise again. I lost about 15 pounds. My skin was glowing from the inside out. I have loved every Perricone product I’ve tried & have amazing results! At 57 people think I’m 45! My problem is that I have run out of all my products that I used to be able to purchase. Alas, my husband left me with all of the bills & I wasn’t working at the time. We are now eparated…pending divorce.So he messed me up financially! I haven’t been able to purchase any Perricone products & nothing else compares to them! Please choose me as a tester! I need to use the products & I will write outstanding reviews! My skin is not glowing like it did when I was using Perricone exclusively! Patti Boe

  39. I would love to try Cold Plasma I have heard so much about it.

  40. I have fine lines and uneven skin tone. Would love to try perricone products after reading the review, especially the cold plasma.

  41. something like that. Actually amino acids, when suspended in nertual solution (such as water) exist as more of a zwitterion, with both an acidic (pH around 2.3) and a basic (pH around 9.6) component. In cosmetics, amino acids are often used as moisture binding agents, which help water stay in the skin. ;P They’re not acidic, or corrosive enough to slough the upper layer of the skin, nor are they large enough to act as an abrasive. So, how DO amino acids exfoliate skin? o_O

  42. I love this product! I don’t find the slight odor offensive at all, in fact I appreciate that the product is not full of perfume. My skin is brighter and smoother and at 65 years old, that is a real plus. People ask me frequently about what products I use because my skin looks pretty darn good in spite of years of sun exposure in my youth. The jar of Cold Plasma lasts a long time so it is worth the expense.

  43. I am in basically good shape at 135 lbs and 57 yrs old, but I ‘m noticing loss of skin tone especially on lower part of arms – crepey! I’m devastated that looks SO old . Otherwise I look about 48-50 but upset about lack of tone in ARMS & LEGS. Can you help?

  44. I am 72 years old and am often told that my skin is beautiful. I wear little to no make-up–usually just moisturizer and occasional foundation–but I’d like to tighten my skin and add some radiance. Being a tester would lead me to appropriate skin treatment to maintain and augment my appearance.

  45. After using a sample of this, my boyfriend literally stopped our conversation to tell me that my skin looked PERFECT. He said it was so smooth and radient and I couldn’t believe it but I kid you not.

  46. I received a sample of Cold Plasma with a Sephora order, and the results were immediate. My boyfriend actually paused in the middle of conversation and said “Your skin looks PERFECT. Like, it is the smoothest most perfect thing I have ever seen. What did you do to it?”

    I kid you not!!

  47. I am about to go into my third month of using Dr. Perricone’s Cold Plasma. I would like to test other products Dr. Perricone offers

  48. I am a 46 year old grandma who loves to mountain bike. I need my face to match my level of physical activity! I would love to have younger looking skin to match how I feel. Have tried many different brands, no good results. Is Perricone MD the one for me finally?

  49. I got a free small sample packet of the cold plasma from Sephora and after 2 days of using that tiny sample, I’m hooked. Unfortunately it’s not in my families budget at this time to order more. I wish though… Bc I love this stuff. It’s amazing.

  50. I have heard about this product, all good things and i would like to give it a try we only have our skin were in so i would like to have the best.
    Thanks. My skin is getting older