Perricone MD – Cold Plasma



You’re an individual with unique skin care needs. Even if you and another person are both clinically healthy, one of you may need more of one type of nutrient than the other does. With this concept in mind, over the course of five years in collaboration with physicists at Los Alamos Laboratories, Dr. Perricone developed Cold Plasma, a revolutionary product to help enhance your current anti-aging routine through the power of biochemical individuality.

What is biochemical individuality, and how does this revolutionary product, Cold Plasma, work?

Learn more:


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Correct the 10 signs of aging

Cold Plasma is a universal skin care product; suited for anyone, no matter how old your skin is, what your skin type is, or whether you’re male or female.

Cold Plasma works through a patented ionic (i.e. charged particles) suspension carrier system which allows for your skin to extract from Cold Plasma’s formula according to your individual, unique needs. This personalized system, called biochemical individuality, is a self-selection process charged by phospholipids, major cell membrane components. Phospholipids are fat derivatives which help lock in moisture, because phosopholipid bilayers have hydrophilic (attracted to water) heads facing outward and hydrophobic (mix poorly with water) tails facing inward toward each other. The phospholipids in this formula help direct needed nutrients where they can be effectively used through the cell membrane. This also means, if any of the ingredients aren’t needed, they just won’t be utilized.

Check out the latest Perricone sale for $10 samples!

Cold Plasma works through this system to deliver optimal nutrition to skin cells to help skin achieve a healthy, glowing, youthful appearance.

It does so by helping combat the 10 signs of aging, which include:

  1. Firmness
  2. Elasticity
  3. Clarity
  4. Radiance
  5. Smoothness
  6. Texture
  7. Redness
  8. Blotchiness
  9. Fine lines and wrinkles
  10. Dryness



Beyond the unique delivery system, the key sciences behind this product include:

  • Advanced neuropeptide technology to give anti-inflammatory effects, which assist in slowing the 10 aforementioned signs of aging.
  • DMAE to help stimulate nerve function, thus causing muscles under skin to tighten, providing a lifted and firm appearance to sagging skin.
  • L-tyrosine, an amino acid, brightens skin to help radiate a youthful glow.
  • DHA, an essential amino acid, to support the preservation and hydration of skin.

cold plasma


Cold Plasma contains no:

  • Parabens
  • Fragrance
  • Sulfates
  • Mineral oil
  • Artificial colors or fillers



How to apply Cold Plasma

According to Dr. Perricone’s recommendation, in the morning and evening:

  1. Cleanse skin, first
  2. Apply Cold Plasma
  3. Put on any Perricone MD treatment and/or moisturizer to finish




Recent reviews

Can it get any better? – “I’ve been using Cold Plasma since its exclusive debut on QVC and have been amazed that my skin could actually look any better after five years on Perricone products. Yet it does! Brighter, firmer, smoother…all this and more…” —From blog.perriconemd.com

What a difference! – “Tone and texture has evened out, pores (which I was told mine were small, but were visible to the naked eye), are virtually diminished, I can only see them when I use the dreaded 10X mirror to pluck my eyebrows. The price is high, but the product goes very far, I am sold on the product, and will definately stay on the auto-delivery plan. I notice I am using less make up, so I figure the money will even out, in the long run. Its nice to get up in the morning and debate on even bothering with the make up…” —From QVC

Can’t live without it – “Great product, I highly recommend! I’m 40. I noticed a change in my skin tone, radiance and the big one– It softened my lines and wrinkles right away!!! This is a product I can’t live with out.” —From QVC


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680 Comments • Comment to become a Perricone tester!

  1. would love to try cold plsma.. heard great things!

  2. I am 57 years old and recently went through a procedure to remove a large basal cell carcinoma mass from my nose. In treating the affected area I’ve noticed that my skin has started to sag, change texture and color, it seems overnight. I would like to test your products to slow the process of enlarging pores and rehydrate my skin. I’ve heard rave reviews about your products and would like to see it for myself.

  3. I am nearing the big 6…0…& am fortunate that apparently ‘I do not look my age’…that being said, in my research I have come to realise that a product that includes the ingredient DMAE would be helpful with regards to firmness & perhaps even muscle tone…I have never tried any of Dr. Perricone’s products but see that the Cold Plasma product & neck products may be the answer…& am looking forward to giving them a try.

  4. I am 52 years old and my skin looks very old.I would LOVE to see if cold plasma would work for me.

  5. Lovely blog. I’d love to try that Cold Plasma!

  6. I love Perricone products and cold plasma is great – mostly I need this product to give to my young daughter so as long as she eats healthy takes her vitamins and uses Cold Plasma she will never have an skin problem to fix. The Perricone approach to beauty and health is the best.

  7. Would love to test your products!!!!!

  8. I have dark circles under my eyes, and under that I have bags. They have gotten worse w/the years. I am 60. PPL say I look 45-48 ish. The eyes give me away though. Can you help w/something for this. I have tried everything on the market and w/them not working at all and skin sensitivities, NOTING has helped.
    What to do??!!! :-)
    Thanyou!

  9. With the help from sales person at Sephora, I purchased items from Peter Thomas Roth, Dr. Brandt, and Dr.Perricone. I was most impressesd with Dr. Perricone’s skin care and plan to add the cold plasma to my list, plus the advanced eye firming cream. I am 74 and plan to continue to look in my 50’s.

  10. I’m 56 years old and I feel like my search for a great line of products is over. My skin feels back to normal and glowing again with some of Dr. Perricone’s products! Living in the desert is challenging for my east coast skin which drinks in Dr. Perricone’s products without irritation. I’m now following the diet and would love to experience the Cold Plasma ingredients on my skin.

  11. I am 37 and experience acne, sensitive skin and the beginning signs of aging. I would love to try this product to combat current skincare issues and ward of future negative showings of age.

  12. I purchased some products on the Perricone website and received Cold Plasma as a sample with my shipment. I am hooked! I have some acne scaring and uneven skin-tone and the tone and texture improved immediately with this product. It’s so nice to see results and find a product that delivers on it’s promise.

  13. Love cold plasma only after a few days!

  14. Have tried the concentrated restorative cream . Made a huge difference in skin tone and texture . Can’t wait to try cold plasma

  15. Sounds divine!!! Would love to try it!!

  16. I LOVE cold plasma. I got a sample from Sephora and was amazed at how it made my large pores almost disappear after one application. I wish I could afford it. It is way out of my price range. It may have to go on my wish list for Christmas.

  17. I have seen this product advertised on several blogs, and it looks great. I am now fifty, and I feel like it’s important to take proper care of my skin, before it’s too late. I have always used drugstore brands in makeup and skincare, but I now see the difference when I use high quality products.

  18. i am in my thirties and am having terrible skin problems…rosacea, acne, dermatitis. i tried the dermatologist, but her suggestions made it worse! i have tried many department store/md brands that seem to work for a few weeks and then stop. i would be really interested to see if perricone products would be the solution for my skin care woes.

  19. hello DR…..I am a 70 yr. old women who definitely does not want to look her age. I am very active and have tried so many prooducts on my face,neck, arms and etc. I’d love to try your product and will gladly purchase it if works. Best wishes to you and your work.

  20. Love, Love, Love Cold Plasma face and eye – excellent product. If you have tried a zillion products, and spent endless amounts of money looking for something that makes your skin feel like skin….this is a must try!

  21. Need this for my neck if it works like im reading I have a bit of sagging loose skin on my neck. Have been using Strivectin and have seen results would like to see. better .

  22. Like that Cold Plasma is non-greasy and light. Feels nice going on the skin and sinks in well. Have noticed more radiance and hydrated skin. I use this every evening and wake up pleasantly surprised.

  23. hi, can i apply cold plasma &/or high potency evening repair on my face after i had a diamond peel? thanks, and more power.

  24. Tried cold plasma( sample from Sephora) on my skin. The effect seen next morning. Excellent product!

  25. Cold Plasma is my spa treatment at home after a long day of being a boss, wife, and mom.

  26. Wow- this cream sounds fantastic! I’ve had a hard time finding a good anti-wrinkle cream that doesn’t break me out. I definitely need to try this one out!

  27. I would love to be a product tester for Perricone MD.. I have been using Obagi products for a little over a year and I’m growing concerned that this may have long term damaging effects. I spoke to a friend who raved about these products. I would love to try them.

  28. The cold plasma is the only product out of dozens that I have tried at various price points that literally erases all of my visible signs of aging, particularly the fine lines around my eyes. It is an amazing prodeuct.

  29. I am 55, my skin is not bad for my age don’t smoke and exercise but it is 55. this product was amazing . I tried it first asa sample in a Mecca store here in melbourne. instantly i saw a difference. Love its light weight texture and the fact it works. got the eye cream now

  30. Have always been complemented on my skin,recently felt that I had lost some vibrancy, I received a sample of Cold Plasma and tried it immediately, it has been two days now and even my teenage daughter has commented on wonderful my skin looks. It looks and feels great.

  31. I have mild-moderate discoid lupus. I really need a skin care system. That with help with the texture issues caused by this auto immune issue and the overall againg of my skin.

  32. This is the best skin care I have ever used. It may be expensive but the results are over the top. In the long run the price and the cost is worth every penny. So don’t delay use Perricone it is by far the best skin care on the market!!!!
    Enjoy…

  33. Loved the sample of Cold Plasma that I got from a makeup website. Really noticed the difference in my skin.

  34. I am reading Dr. Perricone’s The Perricone Promise (I also have The Wrinkle Cure)& I really think I have found the solution to my cronic sleep disorder!!!!! I am a ’sugaraholic’ & what I have read what sugar does to your system is astonishing!!! I am just starting the 28 day plan, so I am praying that this will help my sugar cravings as well as my ’sleep problem’!I also now believe that this is why my skin is so dull & my marionette lines seem so prominent!! The only thing missing from the ‘plan’ is the neuropeptide supplement & neuropeptide cream….so maybe I will be lucky enough to win a jar of Cold Plazma to go along with my road to recovery!!! Thank you Dr. Perricone for leading me down the right path!!! :) <3

  35. I saw Dr Perricone on the Dr Oz show and related to him on the diet he was proposing. My husband and I changed our diet in January to something very similar. For the month of March we were entirely vegan. We were trying to regain our health as we were sick and coughing for months on end due to allergies. Our coughs are gone, blood pressure down and we have both dropped 20 pounds. I only learned of Dr Perricones skin care when I was online looking for his books. I would love to try the products before buying as my skin is very sensitive. Most products break me out. However I need some help. I feel too healthy to have all of the fine lines I am gathering on my face. I have a blog. If this product is as good as the reviews say, I will promote it!

  36. It is important for me to take care of my skin. After reading about your cold plasma, I can not wait to try it. It sounds like everything I am looking for in a skincare product. Most people think I am in my early 30’s and are shocked when they find out my children are in their 30’s. I am actually 55.

  37. Looking forward to lookin’ good!

  38. I have tried the sample cold plasma and immidiately noticed a difference. Its funny i have telling people about the metabolic diet and my results lost 6 pounds in 7 day..i am back on it..want to lose 10 more pounds..being very good. on top of that i have been applying cold plasma everyday. Somone that had not seen me in a while and knew i was on Dr. Perricone told me ” Dr. Perricone is workign for you” your skin looks great!. Wow..this from a guy…as we know guys dont tend to notice alot of things..
    I am sold on the science… may i have more samples pleaseeee…

  39. Hi, I would love to try your products

  40. Charged particles in a suspension solution, I think I get it,Sounds interesting.

  41. I would love to test your products! I have tried products in the past for a word of mouth company, to try and test out new products and “spread the word” about them. Your no foundation foundation and Cold Plasma sound amazing! Also, the coq10 is great! I am currently taking it, (for just a week) and have already seen results! Anything you need someone to test I would love to try! Thanks!

  42. i would love to ty some of dr. perricone’s cosmetics. i am 72 yrs. old and look abt. 50, i use the no foundation foundation and i love it. a lady at my church told me i look awsome when she found out my age. thank you.

  43. This moisturizer works great with my oily, aging skin. The smell is a bit off putting when it’s first applied, but seems to dissipate fairly quickly. I’ll be curious to see if the eye cream works as well.

  44. Very glad to see parabens are coming out of perricone products. My dermatologist advised me to avoid them with a vengeance b/c of my sensitive skin. Really excited that Super and Cold Plasma can be in my shopping cart now. Hyper hydrator is the best new thing out there!

  45. This stuff is amazing! My skin looked radiant and supple after only a few days. I got a free sample with a purchase from Sephora and squeezed every little bit out.
    The price tag is a little much for me.

  46. I am a rock climber and love to kayak, hike and generally be outside in the elements. I am a 58yrs old, an artist and grandmother. I have used Perricone activator and am pleased with the results. It would be interesting to try the plasma product.

  47. Good.
    Your Blog is having a very good content and language, which is really admirable.

  48. Although I have purchased the cold plasma before, I have not had the opportunity to use it! A friend of mine raved about it so much that I gave it to her unopened. I did try a sample packet, but it was only good for one application; felt good, looked good but that was just a one time deal. I would love the opportunity to try it for a slightly more extended time period.

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  50. Can’t wait to try it. Sounds awesome! Please send me a test sample. I want to share this with all my friends.

    I am about to become a Grandmother and am very excited about the life change but do not in any way want to look like a Grandmother.

    Help! This might just be my answer!