Is There a Wrinkle Cure? Dr. Nicholas Perricone Says Yes

Many surrender to the idea that wrinkles are an unavoidable result of years gone by. However, Nicholas Perricone, M.D. looks at aging differently. He thinks there may just be a wrinkle cure.

He says, “Wrinkled, sagging skin is not the inevitable result of growing older. It is a disease and you can fight it. You can look your best, feel your best, and enjoy beautiful skin and optimal health every day of your life.”

How is this possible? Is there really a wrinkle cure?

Read on to find out what causes aging and why Dr. Perricone stands by his belief.

This article will discuss:

Inflammation: The Culprit

Dr. Perricone concluded after years of research that the underlying cause of wrinkles is inflammation. Rather than redness visible to the naked eye, inflammation is microscopic irritation in cells that leads to cellular damage. What this means for the skin is problems like breakouts, dullness, sagging, and of course, the subject at hand, wrinkles. Inflammation is also the single greatest precipitator of age-related diseases such as heart disease, diabetes, Alzheimer’s, arthritis, and certain forms of cancer.

Before finding out what causes inflammation, watch Dr. Perricone personally discuss what inflammation is in the video below:

What triggers inflammation?

Cellular inflammation is caused by a variety of external factors, such as a pro-inflammatory diet and overexposure to ultraviolet light. Foods that are pro-inflammatory include all sugars, processed foods, pasta, breads, pastries, baked goods, and snacks like rice cakes and pretzels.

Dr. Perricone treats inflammation in 3 ways, through:

  1. Diet
  2. Nutriceutical supplements
  3. Cosmeceuticals

Through this 3-tier program, inflammation can be stopped, slowing down the aging process and reversing existing damage.

Anti-inflammatories: The Wrinkle Cure

If inflammatory damage at the microscopic level is the cause of wrinkles, the opposite, anti-inflammatories, can help cure. Antioxidants, for example, are natural anti-inflammatories that protect against inflammation that causes cellular damage.

Where can you find anti-inflammatories?

Diet and nutritional supplements can help provide the body with the anti-inflammatories it needs to stay youthful and strong. At the basic level, an anti-inflammatory diet involves eating protein, antioxidants, and essential fatty acids, as well as drinking 8-10 glasses of water a day. Meanwhile, nutritional supplements that include natural anti-inflammatories also helps work against damage.

Additionally, cosmeceuticals formulated with antioxidants like alpha lipoic acid and other anti-inflammatories, like DMAE, can act as a wrinkle cure by treating from the outside, in.

Want to learn more about Dr. Perricone’s wrinkle cure? The Wrinkle Cure (Warner Books 1998), one of Dr. Perricone’s New York Times #1 best sellers, is your guide to wrinkle-free skin for a lifetime. It provides an in-depth background on his research behind his Inflammation Theory of Aging and explains the formulations behind his anti-aging products.

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127 Comments • Please comment below


  1. I subscribe to the natural solutions when it comes to my health, diet and skin care and wouldn’t dream of going under the kife, ever! But lately I am noticing the wrinkles and the sagging on my face and it is really depressing to me. Especially because I work so hard and am so faithful when it comes to eating right and drinking good clean water. I believe that your products will help me and I would love more than anything to try them!

  2. I subscribe to the natural solutions when it comes to my health, diet and skin care and wouldn’t dream of going under the kife, ever! But lately I am noticing the wrinkles and the sagging on my face and it is really depressing to me. Especially because I work so hard and am so faithful when it comes to eating right and drinking good clean water. I beleive that your products will help me and I would love more than anything to try them!

  3. I have tried everything on the market for the lines above my lips…even Botox….HELP….I would LOVE to test your product. I love Dr.Perricone and know that he is at the cutting edge of research on skin solutions. Rita

  4. I’m 66 yrs old and have neved done much to care for my skin. now I’m paying for the little I did to my skin with age spots, wrinkles and dull skin. I like to test your products, learn how to prevent wrinkles, and make me look youthful again. have a beautiful day! Lola

  5. I like to be product tester to try them please. Thanks.

  6. I’m a 61 year young woman in the midwest. I would love to test your products. Thank you for your consideration.

  7. I am 62 years old and have led an active lifestyle. I feel I have the “right” diet about 75% of the time. I have used Obagi products over the last year. I’ve taken good care of my skin but would love to see if the Perricone products could make a difference in my skin. Thank you for your consideration.

  8. I am over 50 and have an on-going breakout problem and yet my skin is dry and sensitive! I would LOVE to try your acne products…especially since they also address anti-aging issues!

  9. if theres a cure, i need the cure

  10. I am 51 years of age and have the best skin I have ever had due to your products.I love to read, write, and research and possess attention to detail. Consistent use is imperative for any product; therefore I believe I would be a good tester. Thanks for the consideration!

  11. I have multiple sclerosis and I have read in many places that some believe that it has something to do with inflammation…I am not sure what exactly what though.
    Maybe this is why I have prematurely aged even though I do not drink or smoke, I have saggy, very wrinkled, blotchy and acne filled skin. I am 22.

  12. Would love to try your product, almost 40 but after years of being out in the sun, and we all know how much sunscreen we used in the 80″s!

  13. I was raised without a mother or a sister and no-one ever taught me how to take care of my skin, apply makeup or do my hair. I would love to try your products. Thank you!!

  14. I would love to try some of these products and become a Perricone tester. I have heard nothing but good things about Perricone products, and I’m so escuted to start trying it myself!

  15. I would like to be a product tester also

  16. I have tried many products I am 58 years old and the lines and wrinkles are setting in. I am anxious to try your product.

  17. I have always noticed that when I eat fresh fruit and veggies my skin looks better vs. when I go out and have a long night out w/ no sleep and plenty of alcohol. I always thought it was my imagination until I started researching your philosophy! SO amazing! I started eating very fresh, drinking a ton of water and green tea, and with in one week, I saw my mom who comment, “your skin looks like it is glowing.” I can’t wait to one day add the products into my routine and tell everyone that asks what I use!

  18. I have been fighting with wrinkles for year snow and am desperate for some help! Hope this works!

  19. I am just noticing my skin starting wrinkle and sag. I cannot wait to try Perricone products. I have only heard wonderful things about them.

  20. If there is a wrinkle cure, I would love to get it!

  21. Your products sound interesting, and I would like to try them!

  22. I just love the way diet and proper skin care come together with thoughtful science to the goal of making each of us more glowing and wonderful!

  23. I would love to test your products. Sign me up!

  24. I have read a couple of your books and would love to test some of your products.

  25. Because I modeled throughout 1975 until recently, my husband thinks that my standards are too high. He may be correct, however, I insist that women and men must take care of themselves and I use the best products to care for my skin. Not necessarily the most expensive but the best. I would appreciate the opportunity to discuss this opportunity with you. You may email me at the above address

  26. I have read about your product line, and think your approach to aging skin makes sense. I would love to be a product tester. Thanks!

  27. I’m in desparate need of some anti-wrinkle aids and some eye lifting ones as well – I’d LOVE to be a Perricone tester!

  28. just hit double nickels and must try your products to stay “young”!!!

  29. i just hit double nickels and after looking younger then all of my friends for many years- it seems i’ve finally caught up with them. getting the howdy doody lines and “crinkles” above the lip along with lines around the eyes and the same tic-tack-toe board on my forehead(along w/ furrows in between the brows)- please help!!!

  30. Yes,sign me up I will try always looking for good is defintely dryer in 40′s and needs alot more tlc.

  31. I am now 61 & would love to try your products. I have read such good things about them & would be a good tester.

  32. i look like a bassithound and can not seem to get that to change. i would enjoy trying your product.

  33. I am looking for a great skin product and Perricone seems to be the one. I would love to try and see how it will help my wrinkels.

  34. I would love to become a tester of your product to reduce my wrinkles!!!!!

  35. I’ve tried a lot o products and have not been satisfid with any of he products and wouuld love to become a tester!!!!

  36. I would love to become one of your testers – I’ve heard nothing but great news about your products!

  37. I do have some wrinkle concerns, especially around the eye area….even tried Botox! I would love to try your products!

  38. I would like to become a Perricone product tester. Thanks.

  39. I am looking for a new skin care routine with absolutely no luck! I would love to test your products!

  40. Very interested in trying your products to see if they can help me.

  41. I am 30 and just starting to think about skin care. I would love a chance to try your product out.

  42. I have heard so much about this from reading articles. Would love to be considered for this. I am 55, feel 38, but look worse. :(

  43. I am 51 and starting to show aging, can’t wait to try your products.

    Thank you,

  44. I have more than my share of wrinkles and would love to see them go bye bye. I would love to e able to test for you and tell my friends about your products.

  45. I would love to try this product, my skin looks dull and is starting to show age.

  46. Oh my gosh I have done this before for another company and not only is it fun but its a great way to promote the products tested to family and friends. Yes sign me up.
    Grins N Giggles

  47. I have RA and am on Remicade Infusion. My bloodwork says my sed rate is highly elevated. Does this mean I will have more wrinkles if you are saying its inflammation that causes some wrinkling? I have been using your ceramic skin smoothers for my face and eyes but now my problem is the lines around my mouth and some on my chin. I would greatly appreciate becoming a product tester so I can figure out what works best in that area. Thanks.

  48. I know alot of people are concerned about the crow’s feet around eyes, but my main problem is the lines around my mouth. I used a straw alot to avoid staining my teeth and then one day woke up and saw all these lines! Can anything help? I would love to become a tester for your products. I am on a tight budget and would appreciate knowing for certain if something works before I bought it.

  49. I never really learned to take care of my skin until later in life. Now, what was taken for granted in my youth is important. I would be happy to test your products and provide honest feedback as to their performance.

  50. I would be thriled to try your product. Just entering my 50′s and after 2 battles with cancer my skin has been ravaged.