Is There a Wrinkle Cure? Dr. Nicholas Perricone Says Yes

Many surrender to the idea that wrinkles are an unavoidable result of years gone by. However, Nicholas Perricone, M.D. looks at aging differently. He thinks there may just be a wrinkle cure.

He says, “Wrinkled, sagging skin is not the inevitable result of growing older. It is a disease and you can fight it. You can look your best, feel your best, and enjoy beautiful skin and optimal health every day of your life.”

How is this possible? Is there really a wrinkle cure?

Read on to find out what causes aging and why Dr. Perricone stands by his belief.

This article will discuss:

Inflammation: The Culprit

Dr. Perricone concluded after years of research that the underlying cause of wrinkles is inflammation. Rather than redness visible to the naked eye, inflammation is microscopic irritation in cells that leads to cellular damage. What this means for the skin is problems like breakouts, dullness, sagging, and of course, the subject at hand, wrinkles. Inflammation is also the single greatest precipitator of age-related diseases such as heart disease, diabetes, Alzheimer’s, arthritis, and certain forms of cancer.

Before finding out what causes inflammation, watch Dr. Perricone personally discuss what inflammation is in the video below:

What triggers inflammation?

Cellular inflammation is caused by a variety of external factors, such as a pro-inflammatory diet and overexposure to ultraviolet light. Foods that are pro-inflammatory include all sugars, processed foods, pasta, breads, pastries, baked goods, and snacks like rice cakes and pretzels.

Dr. Perricone treats inflammation in 3 ways, through:

  1. Diet
  2. Nutriceutical supplements
  3. Cosmeceuticals

Through this 3-tier program, inflammation can be stopped, slowing down the aging process and reversing existing damage.

Anti-inflammatories: The Wrinkle Cure

If inflammatory damage at the microscopic level is the cause of wrinkles, the opposite, anti-inflammatories, can help cure. Antioxidants, for example, are natural anti-inflammatories that protect against inflammation that causes cellular damage.

Where can you find anti-inflammatories?

Diet and nutritional supplements can help provide the body with the anti-inflammatories it needs to stay youthful and strong. At the basic level, an anti-inflammatory diet involves eating protein, antioxidants, and essential fatty acids, as well as drinking 8-10 glasses of water a day. Meanwhile, nutritional supplements that include natural anti-inflammatories also helps work against damage.

Additionally, cosmeceuticals formulated with antioxidants like alpha lipoic acid and other anti-inflammatories, like DMAE, can act as a wrinkle cure by treating from the outside, in.

Want to learn more about Dr. Perricone’s wrinkle cure? The Wrinkle Cure (Warner Books 1998), one of Dr. Perricone’s New York Times #1 best sellers, is your guide to wrinkle-free skin for a lifetime. It provides an in-depth background on his research behind his Inflammation Theory of Aging and explains the formulations behind his anti-aging products.

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127 Comments • Please comment below


  1. I would love to be a product tester

  2. I have been wearing sunscreen daily since I was 18 years old. I’m now 41 and get mistaken for a high school student. An ounce of prevention is worth a pound of cure.

  3. I am really interested to see how Perricone will help me with my wrinkles. I would like to try and see.

  4. I have tried all the products and have not seen one difference in my fine lines and wrinkles, even the product that says 100% of users have seen an improvement. I’d love to test your products to actually find something that works.

  5. I want to be a tester

  6. I wish I had known the benefits of taking care of my skin earlier. At 48, I can see the error of my ways. I would like to become a product tester.

  7. I am always looking for great skin care products. I would be interested in being a tester for Perricone products.

  8. I am just 29-years-old. Yes,I have to emphasize my own age to remind myself that I have to be nicer to my own skin- I have been reminded by it everyday by the WRINKLES! They appear whenever I smile – mainly at the ends of my eyes, some are around my nose. I am just 29 – I would love to test your product to see whether Dr.Perricone is my saver!

  9. I am extremely interested in testing any of your anti-aging products–thanks!

  10. I have approached the stage in life when collagen growth and other cellular activities slow down. Have specific issues from the neck up that could benefit from your products. Would be honored to be considered as a tester.


  11. would love to try your products . heard many great things.

  12. I’ve had pretty good skin up until about a year ago when I turned 45. Lines are appearing next to my eyes, my smile lines are more pronounced and my ‘anger line’, (my kids call the line between my eyebrows my anger line), is becoming more permanent, even when I’m not frowning. I’d love to test these products to see if I could erase a little time off my aging face!

  13. am trying to find a product that works. am in my thirties and looking for a product that works for my skin. read good reviews on your products and am curious to try them.

  14. I can’t wait to receive my sample to test your products–I’ve read rave reviews!

  15. I am 54 years old and have a few fine line wrinkles. I have been trying different products to help reduce them. I would love to be a tester for some anti age products.

  16. I have heard great things about Perricone products. It would be a great opportunity to be a tester for these!

  17. does this product really work? does anyone have experience?

  18. I’m 61 and have very few wrinkles, but my skin in sagging and the lines between my nose and mouth are getting very deep. Do you have a product for that? I’d love to test it. Do you think I need retinol?

  19. i am really starting to notice crows feet and dark circles under my eyes. any help/advice would be appreciated

  20. I am in my 60s. Five years ago my plastic surgeon was ready to do cosmetic surgery to remove some wrinkles, etc. resulting from aging. I convinced her to let me try the Perricone anti-aging diet/supplement approach first and as a result she is now a believer and recommends this approach in her practice! Would love to be a product tester!!

  21. At 31 years of age, I already have an overabundance of wrinkles, especially around my eyes! I enjoy gardening, and as such I spend a lot of time outdoors. Keeping my skin well hydrated, and hence decreasing the number of wrinkles, is a constant battle. I would like to test your products to help combat these skin issues.

  22. I’m always trying to lessen the look of my wrinkles, especially around the eyes. I’d love to try any products.

  23. I would love to tes your products!

  24. I will anticipatingly be scoping out this site and learning all I can about the Perricone products. Looking forward becoming a tester and to hearing from you soon and thank you!

  25. I would not use anything else. My friends have difficulty guessing my age. Thanks so much.

  26. I have an interest in anything that will help my skin to look it’s best, would love to be a product tester for your company, thank you for your consideration.

  27. Wow. After menopause hits…well, so does the stress…and wrinkles. I’d love to give this a try.

  28. would love to test your products

  29. I want to be a product tester!

  30. I’m 28 and seeing my skin start to change, make up seems to make wrinkles stand out even more. I’d love to try Perricone.

  31. I have read several of Dr. Perricone’s books and would love to try some of his products. I am dealing with acne and aging.

  32. I would be interested in being a product tester!

  33. I would love to product test your products. Unfortunately, I am starting to get “the wrinkle effect”

  34. I’m 40 years old and hate that I am getting wrinkles, as is everyone my age. I would love to be a product tester.

  35. I would love to become a product tester for you! I live in New Mexico and the arid conditions here have wreaked havoc on my skin for the 6 years I have been here. I used to have such beautiful skin, and no matter what I try these days I do not get the results promised. I am 35 years old. I try to maintain a healthy diet and lifestyle, keep myself well hydrated, and feel that I woudl be a great product tester for you. I would be willing to provide detailed feedback, and am certain I can meet any requirements you would have for me. Thanks!

  36. I would be interested in being a product tester for some of the anti-aging products.

  37. im very interested in skin care and the cutting edge ingredients used in the perricone line…i would very much like to be considered to become a product tester.

  38. I am in my early 60′s and feel that my skin looks pretty good for my age, but anything I can do to prevent more wrinkles would be great!

  39. I would love to become a product tester and share my experience with readers of my blog ! Especially interested in skin care products:)

  40. I have tried a few of Perricone’s products anad have loved them. I would love to become a product tester to give opinions and help others decide what’s right for them.

  41. I’d love to be a product test!

  42. I would love to be a tester for your products. I can’t wait to receive my free sample.

  43. I’d love to be a Perricone tester!

  44. I have heard wonderful things about this product and will share this information with all my friends.

  45. I’d love to be a product tester!

  46. I watch QVC and am interested in your products and would like to try them.What a treat to be able to try something on my skin in my own home and see how true the statements are or are not about skin and how I can maintain a healthy look and feel to my skin. That is the secret to looking good,having health skin.

  47. WOW! I can’t believe that there are no comments on the claim that sagging, wrinkled facial skin is a desease that can be fought. Aside from being 60 years old, I have recently lost 100+ pounds and my face shows the effects of both. Also, I live in Southern California and have the “sun damage” going on. If there is a way to combat these problems I want to know everything about it! I will be studying this site and learning all I can about the Perricone products. Hope to hear from you soon and thank you!

  48. I am very interested in your product line and would like to become a tester.

  49. Im alway’s looking for great skin care. I would be proud to test your products. thankyou

  50. I have not hit my 30s and see wrinkles. I have not been that nice to my skin and wish to satrt now jsut not sure how to go about it. Please help me!!!!

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