How to Care for Your Face with the Top 3 Wrinkle Creams

Finding the best wrinkle cream for your face can be a difficult feat. There are many things that go into the decision.

Whether you are looking for a, an anti-aging cream, a restorative cream, or a complete face lift cream, there is something for you.

To get started, check out this list of Dr. Perricone’s Top 3 Wrinkle Creams:

The Best Anti Aging Wrinkle Cream

Cold Plasma is the best proven anti wrinkle cream. After 5 years of research, Dr. Perricone’s creation has helped so many fight the hands of time.

How to Apply

Vanity Fair interviewed Dr. Perricone to find out more on this groundbreaking creation. It is a perfect addition to your skin regimen and not hard to use to care for your face. Dr. Perricone recommends applying on cleansed skin morning and evening. This alone, he says, may not be enough moisturizer for some, so follow with a Perricone treatment and/or moisturizer to boost benefits.

The Results

  • 94% of users said they felt it gave their skin all it needs
  • 89% of users said their skin never looked healthier or smoother
  • 85% of users reported instant results
  • 79% of users said it worked better than anything else they have used

The Best Restorative Wrinkle Cream

Another anti aging cream that has stirred the cosmeceutical world is Perricone’s Concentrated Restorative Treatment which is clinically proven to help resurface skin’s texture and minimize discoloration, revealing radiant and healthy looking skin.

And the best part? It’s all done while you are asleep as this potent night treatment does wonders after application before you go to bed.

How to Apply

For best night results, Dr. Perricone recommends applying to the face, neck, and decollete in the evening in a gentle circular motion and massaging along the hairline and behind the ears.

The Results

  • 86% of users reported diminished appearance of wrinkles
  • 85% of users reported increased skin elasticity

The Best Face Lift Wrinkle Cream

Finally, the best face lift wrinkle cream award is given to High Potency Amine Complex Face Lift. It seems obvious because of Perricone’s use of the highest concentration of his anti-aging ingredients yet (more than the previous Amine Complex Face Lift). The additional ingredients are used to more effectively deliver a lifted, tightened, defined, contoured, and radiant appearance.

Try Perricone for as little at $10.

High Potency Amine Complex Face Lift compared to Amine Complex Face Lift:

  • 16% more DMAE
  • 700% more Vitamin C Ester
  • Pycnogenol

How to Apply

Dr. Perricone recommends applying this light-weight treatment to the face, neck, and decollete after cleansing. Continue treatment to the hairline, back of the neck and ears for optimal firming results. Perricone advises to follow with a moisturizer if additional hydration if needed. For the highest lift, layer Facial Contour Cream over the HP Amine Complex Face Lift in targeted areas in an upward motion.

The Results

  • 87% of users reported their skin felt “tighter”.
  • 83% of users reported their skin appeared healthier and more renewed.
  • 80% of users saw improvements in the appearance of wrinkles.
  • 80% of users reported their skin appeared more luminous.

Now that you know the top 3 wrinkle creams, finding the best wrinkle cream for your face is hopefully not as difficult. Remember whether you are looking for, an anti-aging cream, a restorative cream, or a complete face lift, there is something Perricone M.D. has for you.

Have you tried Perricone products? Do you agree or disagree with this top 3 wrinkle creams list? Share your picks in the comments below.

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4 Comments • Please comment below


  1. Hi Dr. Perricone. I LOVE your products!!! I do have a question, though. Do I use the Sub-D after the Concentrated Restorative Treatment? If so, should I wait any amount of time between applications? Also, my Restorative Treatment cream has become a bit runny. It still feels and smells the same, and I feel the same slight tingle on application. I think it’s fine, but want to make sure. Thank you!

  2. I work as a flight attendant and typically fly 3 trips a month from NY to China~resulting in over 90 hours on an airplane a month!!! I eat well, excercise plenty and drink water but my skin is becoming dry and dull. I saw Perricone M.D. on Dr. OZ and am interested in helping myself bounce back from the uncirculated air that I spend so much time in!

  3. There are so many creams listed on your site and they all sound great… does one know what is exactly right for them. I am 45 and as a nutritionist I eat well, supplement and drink water. I went into early menopause and am now noticing some droopiness in my face and have some lines. Basically I want a mini facelift. Can you direct me as to how to find the best product that will suit my needs. Thanks

  4. I’m currently working on a military base in Iraq. My skin is crying help! I have been living in Florida so the change from humid to dry has my skin flaking and dull. Please let me be a product tester. Using these harsh conditions will be a great test. I can provide photos, reviews, diary; whatever is necessary. Help my skin, please.