Formula 15

Formula 1515 years after his smash hit, Advanced face firming activator (AFFA), Dr. Perricone is at it again and brings you formula 15. Specially formulated with DMAE and Alpha Lipoic Acid, formula 15 is the AFFA of the future. A professional grade of AFFA, Formula 15 is a potent, powerful, and highly efficacious treatment.

Results from consumer testing show that Dr. Perricone’s Formula 15 provided an improvement in wrinkle length, width and depth.


  • 81% demonstrated a measured improvement in their wrinkle length
  • 68% demonstrated a measured improvement in their wrinkle width
  • 75% demonstrated a measured improvement in their wrinkle depth

Formula 15 soften and smoothes the skins’ texture upon application. While doing so, formula 15 restores the youthful glow and suppleness of skin.


The secret

The ingredients of Formula 15 are the key to its success. Formulated with Alpha lipoic acid (ALA), Formula 15 autoxidizes while diminishing wrinkles, discoloration, and fine lines. In addition, this powerful acid in Formula 15 also minimizes puffiness, uneven skin tone, imperfections and pore size.

As well as Alpha lipoic acid, Formula 15 also boasts Dimethylaminoethanol (DMAE) which fights the loss the elasticity common in aging skin. By doing so, DMAE lifts, tightens, and tones the appearance of skin while diminishing the appearance of facial and under eye wrinkles and fine lines.

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12 Comments • Please comment below


  1. Sto’ usando da qualche anno i prodotti del Dott.Perricone creme, sieri,detergenti,li trovo fantastici. Non ho ancora provato Cold Plasma Sub-D dove posso trovare un campione da provarlo? Prima compravo i prodotti nei negozi di Trento, Reggio Emilia ecc Ora mi servo su QVC Germania ma loro non mandono i campioni.

  2. I started using this recently in the AM and I can tell that it is working already. This product caught my eye because I watched a youtube video and the Dr. was talking about post acne skin and how the ALA is great for the issues that people have with this type of skin. Sun damage is also something that I am aware of now because I love being outdoors in the Florida sun, and I want to take care of my skin the best way possible. I can feel this product when I apply and I am in love with the scent. It has been a week and I am very happy with Formula 15!

  3. I started using formula 15 for 3 days last month and my skin turned red, started having burning sensation and continued to burn all day and night. I am usually not allergic to cosmetics or any serums. I have used the perricone md vitamin c ester with no side effects. The redness and peeling stopped after I used triderm. I stopped using formula 15 for a
    Week and my skin was totally back to normal. I tried it again this morning and the redness burning and peeling started again. What’s wrong with this serum?

  4. My oldest daughter came home for Christmas and asked me what I was using for skin care because ,she said my facial skin was “plumped out and glowing”. Itold her all I have been using is Dr. Perricone Citrus cleanser and Formula 15 ,for the previous two months! Iam 53 years old and have been using Dr.Perricone products for 11 years. I couldn’t be happier!Also the lady at the cosmetic counter in the Mall thought I had foundation on my face when I did not! Another compliment to Dr.Perricone!!

  5. DR. Perricone

    Very interested in Becoming a Product Tester. Currently using FORMULA 15, have used for appx. six months, with no visible results. Can You suggest, another Product of Yours to use?

    Thank You

  6. I’m an avid user of NV Perricone products and would love the opportunity to test your new products and be the first to find out if they work as well as your earlier ones. I love what AFFA has done for me so far and am excited about trying out your new products.

  7. I just bought my first bottle of Formula 15. So excited to see the results!

  8. I would LOVE to be a Perricone tester for your Formula 15 and Neuropeptide Moisturizer!!! My best friend uses both of these products and RAVES about them and I’d really love to sample them before I purchase.
    I work in a natural healthcare setting and if these products work I’d love to pass on the word to my patients since your products are made with such top quality ingredients.
    Thank you very much!

  9. I truly believe in the science behind your diets and products.

    I have seen a difference in my face with your neuropeptide face cream and your high potency night repair.

    I still have a problem under my eyes, but I will continue to search for one of your eye products that will work for me.

  10. I am very much interested in becoming a product tester. I just purchased Formula 15 and hoping the results are as dramatic as claimed. I have used the Cold Plasma line in the past. Please do contact me.

  11. I would like to test this product, I tried the new neck serum and was very happy with how great my neck and chest skin looked, so much smoother and healthy looking, great product.

  12. Have you replaced More Than Moisture with another product? I am almost out and was going to replace my bottle.

    Marlene Reddington