DMAE Cream to Lift and Firm Skin

DMAE, an abbreviation for dimethylaminoethanol, is a nonirritating antioxidant base that works to protect cells and rejuvenate skin, often in combination with amino acids and other nutrients.

Studies suggest that DMAE can play a role in making skin firmer, smoother, and brighter, while also reducing the appearance of lines and wrinkles. Dr. Perricone includes DMAE in 16 of his products, ranging from dietary dmae supplements and moisturizers to skin smoothers.

This article will discuss:

  • Effects of topical DMAE cream on skin
  • Who uses DMAE cream?

Effects of topical DMAE on skin

A multi-center, double-blind study designed to determine the safety of topical DMAE found that DMAE facilitated statistically significant improvements in the appearance of the skin. In this study, 156 participants at three different centers applied either a moisturizer containing DMAE or a DMAE-free placebo. Every 2 weeks, for an 18-week period, a dermatologist assessed the participants’ skin and rated improvement on a scale from 0 to 9.

In addition to showing virtually no irritation or dryness resulting from DMAE use, the study also produced proof of its efficacy as an anti-aging treatment. The dermatologists noted significant improvement in:

  • Overall appearance of aging skin
  • Forehead lines
  • Coarse wrinkles
  • Eye area
  • Lip area and smile lines
  • Sagging skin

Perricone MD also performed his own studies on the effects of topical DMAE on various parts of the body that could benefit from lifting and tightening, including the face (particularly the eye area, lips, and jawline), neck, thighs, and buttocks area. He found that treatments that include DMAE both work quickly and provide lasting results. Many people see visible effects within 30 minutes of using a DMAE treatment that last up to 24 hours, and repeated application of the treatment can help create permanent effects.

Face

Dr. Perricone studied DMAE’s ability to increase skin firmness by applying DMAE lotion to one side of 17 participants’ faces and necks. After about 30 minutes, a dermatologist and a cosmetics expert judged the difference between the treated and untreated sides of the participants’ faces. They observed a visible improvement on the treated side that appeared to last 24 hours after just one application.

Once participants began using DMAE cream every day, they achieved even more dramatic results. DMAE promotes the production of acetylcholine, which is responsible for creating muscle tone and movement. Topical DMAE treatments can increase in muscle tone in the face to help create a lifted and more youthful appearance. Some of Dr. Perricone’s patients even reported that the tips of their noses appeared to lift, in response to a newly tightened forehead.

Neck and Jawline

DMAE cream has the same firming effects on the neck and jawline. With just one application, the skin tone of the neck improved. With several weeks of regular application, patients’ jawlines appeared more defined.

Eyes

One of the most visible improvements that DMAE’s skin-tightening ability can bring about is an “eye lift” effect in creams and treatments targeted to that area.

Dr. Perricone’s eye lift cream combines DMAE with alpha lipoic acid and vitamin C ester to treat sagging and fine lines around the eyes and encourage a natural, visibly lifted look to the eyelids and surrounding skin.

Lips

DMAE, in combination with other antioxidants, can also produce a lip plumping effect. DMAE in products like Dr. Perricone’s Lip Plumper helps to increase circulation to the lips, making them look fuller and firmer.

DMAE can also address thin or lined skin around the lips.

Thighs and Buttocks

In stronger concentrations, DMAE may even address dimpling in the thighs and buttocks.

DMAE appears to produce visible improvement in about 20 minutes in those areas as well.

Dr. Perricone talks about his DMAE products in this video:

Who uses DMAE cream?

Dr. Perricone’s research has revealed that DMAE can produce beneficial effects on the skin of people as young as their twenties. DMAE can be a safe and effective treatment for any age and any condition of skin.

DMAE’s ability to help contour skin beginning to lose elasticity, capacity to tighten and tone, and power to help reduce the appearance of fine lines and wrinkles, make it a useful staple in the skin care routines of many types of people. Because of its nonirritating nature, it is even appropriate for sensitive or delicate skin.

As a cosmetic treatment to produce fast results or as a part of a broader anti-aging regimen, DMAE is a potent active ingredient that anyone interested in better skin can use and can be found in many of Dr. Perricone’s skin care products.

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165 Comments • Please comment below

165 Comments

  1. I am a 37 yr old female, use DMAE extract sparingly as a cosmetic detail under my eyes, on marionette lines and lips along with my Cetaphil lotion and see dramatic results. I have spent more money on preperations and have had some sort of skin issue and decided that this was my forte as I am complimented on my skin often.

  2. I am a 37 yr old female, use DMAE extract sparingly as a cosmetic detail under my eyes, on marionette lines and lips along with my Cetaphil lotion and see dramatic results. I have spent more money on preperations and have had some sort of skin issue and decided that this was my forte as I am complimented on my skin often though I have/give no time to it as I have 3 childeren a perfect husband and grandmother with breast cancer to care for. Do your research of course.

  3. I use DMAE extract from a natural foods store,use it sparingly under my eyes/lips/marionette lines with my daily face lotion cetaphil. It smells fishy but after application there is a definite tightening, plump appearance. My face always looks better on the days I use it. From someone who has wanted all of the expensive products to work.. I always go back to Dove sensitive skin soap, Cetaphil lotion and DMAE extract as a plumper, seems to work cosmetically for me, not sure if it has long term effects. Personally after seeing these results I would not waste money on preperations. As a normal precaution you need to research any unwanted effects as DMAE does have some other results when taken internally. This is just a comment from my experience. BTW I am a 37 yr old female, 3 childeren ,loads of stress and get compliments on my skin. This again is only my opinion, hope it inspires.

  4. I use DMAE extract from a natural foods store,use it sparingly under my eyes/lips/marionette lines with my daily face lotion cetaphil. It smells fishy as it should but after my light daily application there is a definite tightening, plumper appearance to my skin. My face always looks better on the days I use it. From someone who has wanted all of the expensive products to work.. I always go back to Dove sensitive skin soap, Cetaphil lotion and DMAE extract as a plumper, seems to work cosmetically for me, not sure if it has long term effects. Personally after seeing these results I would not waste money on preperations. As a normal precaution you need to research any unwanted effects as DMAE does have some other results when taken internally. This is just a comment from my experience. BTW I am a 37 yr old female, 3 childeren ,loads of stress and get compliments on my skin. This again is only my opinion, hope it inspires.

  5. I bought DMAE extract at a natural foods store. I use it sparingly under my eyes/on lips/marionette lines along with my daily face lotion cetaphil. It smells fishy as it should but.. after my light daily application there is a definite tightening, plumper appearance to my skin. My face always looks better on the days I use it. From someone who has wanted all of the expensive products to work.. I always go back to Dove sensitive skin soap, Cetaphil lotion and DMAE extract as a plumper, seems to work cosmetically for me, not sure if it has long term effects. Personally after seeing these results I would not waste money on preperations. As a normal precaution you need to research any unwanted effects as DMAE does have some other results when taken internally. This is just a comment from my experience. BTW I am a 37 yr old female, 3 childeren ,loads of stress and get compliments on my skin. This again is only my opinion, hope it inspires.

  6. If the dmae cream works why are there no before and after photos anywhere on the internet?
    Grace.

  7. At 62 I would like to try anything that Dr. Perricone has to offer.

  8. I have always been blessed to look younger than i actually was until three years ago i underwent tremendous stress and sadly now look older than i actually am

  9. Dr. Perricone,

    I have been very lucky to look younger than my actually age for some time now. Unfortunately, do to tons of stress over the last two years it’s like the brakes hit and many years just caught up with me all at once! I look in the mirror and it saddens me, wrinkles and sagging skin in such a short period of time. Please help!

    Thank you so very much,
    Faith

  10. I have a question…I’m a beautician and very interested in all the benefits of DMAE. My colleague bought it once at GNC store and saw results but than they took them of the shelves and she’s been told that it has a hormoon in it that can cause cancer. I’m wondering if it’s true…I was searching on the internet to look for it but didn’t found anything particular…I’m really interesting in trying your products. I have your book already…

  11. I truly need help, I have premature wrinkling. My mother is very very wrinkled i don’t know if it is hereditary,but i need help on my entire face and neck. Can u Help me, i also need help on my buttock.I would b a perfect canidate
    Thank you seriously.
    Patty

  12. Hello I would like to tighten my buttocks and thighs..

  13. I am 63 y/o male and very curious about your DMAE products. Have read your book, and I like where you’re coming from visa-vie an anti-inflammatory diet.
    Thanks

  14. I just ordered some DMAE cream for eyes right now (just started). I then saw your site. I am wondering if there is a difference between concentrations and/or other products coupled with the DMAE.

  15. It’s great to “hear” about the revolutionary toning effects of DMAE, but where can we “see” the benefits? Are there before\after pictures on this site “showing” visible improvements?

  16. I am a homeschooling mother of six. I need something to make my skin nice that doesn’t require a lot of my time.

  17. Interested in DMAE cream after seeing you on Dr Oz could you tell me what else is in the cream please

  18. [...] DMAE to aid in improving lip contour [...]

  19. Hello,

    I’m almost 30 and my face has to deal with acne + wrinckle problems. Haven’t found a cream that can heal both at the same time. That is why i would be most happy to test and promote your DMAE products.

  20. I am 56 years old, and I have used so many different products. I would like to try this product.

  21. Just ordered Omega supplements. Want to fight the ageing process from both the inside and the outside.

  22. how much are your skin care products

  23. I would like to try dmae cream

  24. Hey Doc.. im 46 and work in the skincare industry , i saw Dr Oz and he raved about the effects on skin using DMAE..working in the industry i get to try thousands of products a yearand alwayz research ingredients and potency to see if they really do make a difference to skin…please consider me for a trialas am extremly excited about this product..

  25. Hey Doc.. im 46 and work in the skincare industry , i saw Dr Oz and he raved about the effects on skin using DMAE..

  26. Eu desejo ser um testador Perricone!

  27. Im interested. In anti wrinkle products & products to help tighten skin
    Thankyou

  28. Hello,
    I am interested in anti aging products. I would be interested in testing some of the products, I live in Australia, but will be visiting the US in October.
    Thank you

  29. Dear Dr Perricone,

    I am 47 and have noticed my skin starting to lose its firmness. I have tried many moisturising and treatment creams – including vitamin C creams that made by Ultraceuticals in Australia, which have been patented by the Commonwealth Scientific and Industrial Research Organisation,and reportedly improve collagen production, through the use of nanotechnology. However, they have only had minor results on my skin. I saw you on Doctor Oz and would dearly love to try your skin firming products. You are not well known in Australia, and so am unsure of where to purchase your products. Could you please advise me of any testing I can be involved in, and anywhere I can purchase your products. Many thanks, Tania

  30. I would lov to try after seeing it on dr oz

  31. IWATCH DR OZ WHEN EVER I CAN. WHICH IS WHEN I SAW DR NICHOLAS PERRICONE. WITH THE MIRACLE CREAM I WAS BESIDE MYSELF.I TO LIKE MANY OTHERS HAVE TRIED IT ALL NOTHING WORKS. SO WHEN I SAW THIS CREAM AND THE RESULTES COULD NOT GET ON LINE QUICK ENOUGHT TO ORDER SOME.IT WOULD BE A PRIVALAGE TO BE A PRODUCT TESTER. HAVE A LOT OF FRIENDS WHO ARE LOOKING FOR THE CREAM. SURE WILL SPREAD THE WORD ABOUT THIS ONE.NOTHING TO LOOSE EVERYTHING TO GAIN WRINKLES AWAY. THANK YOU SHIRLEY.

  32. Hi saw your product on dr oz I have dark sun spots and capillaries around the nose and cheeks and would love to test your products. I’m 50 and housewife. Thanks

  33. Hi,
    I just seen Dr. Perricone on DR OZ.. and i’m really interested nin trying this product thankyou.

  34. I have tried anything and everything that made promises,and I end up have worse skin than before,my skin is very sensitive and dry,I would love to try your product to see if it is as good as it suppose to be

  35. Wrinkles around my mouth and chin. I have tried different products, but nothing has helped. Please help!

  36. I am 59 years old and look like I am in my late 60s. My mother had wrinkles at an early age. So, I hope this is not genetic. Around my mouth and chin are the worse. I have tried so many different products. Please help.

  37. Che bello, ne ho sentito parlare benissimo, ora vorrei provarla!

  38. Mi piacerebbe provare….

  39. I had acne as a teenager and at 68 still have blackheads. I have the scars from Acne which I am very self-conscious of. When I followed Dr. Perricone’s diet I felt the best I have ever felt on any diet I have tried. His products that I have ordered off the television were to die for. I LOVE them. Today, I am looking again at starting the Perricone regimen and would like to be a product tester. I am on a fixed income and can’t get all the products that I need (at this point.) thank you. Kathy B

  40. I suffer the embarrassment of rosacea. I have tried so many creams, and had facials after facials, and NOTHING has ever helped to improve my skin. I am 65, and have fine lines, deep wrinkles, redness, large pores. I’m to the point where I have become depressed, not going out in public because I think my face is where people look first. I feel people are turned off by my skin condition, because when I encounter anyone, they do not look at me. I feel very unattractive. Please help me I would like a very simple skin care regime. Creams with DMAE sound marvellous. I think I finally found a cream that can do wonders for my skin. I want to have beautiful, glowing skin, so I can go out and show my face, and be proud of who I am. I want to be comfortable in my own skin. I am desperate, please send me a sample of a cream that you would be good for starters. Is there ONE moisturizer that I can jus use morning and night? I am on a fixed income, so I cannot afford expensive products. Please help I want to live out my final years in radiant skin. I want to feel beautiful, and I want to look people in the eye. Should they ask what I have done for my skin I would be most happy to promote your product for you. I live in northern Canada in a remote village. Thank you, Dr. Perricone. Thank you.

  41. This seems too good to be true. I have used so many different products with disappointing results. I can hardly wait to test this out, it sounds like a miracle.

  42. i would try this cream if it is free and approved by usda……

  43. Hi, I am a mother, home maker and work in the health care field. I am a young 39 and feel pretty good about my appearance still. But, when I had my son 19 years ago I made the decision to not have anymore children. I began recieving the Depo shot and gained a ton of weight. After 8 years I realized that no matter what I did as far as diet and excercize, I couldn’t lose the weight. I had ballooned to a size 18-20. I felt horrible. So once I got off Depo and had a Tubaligation I started to lose. Then I platued and couldn’t lose anymore. Last year in 2011 I picked up a new and healthier diet plan and with my job I do, I walk a lot. So I’m again losing. Now here comes the problems. I have lost so much weight that my skin literally hangs. And its the worse on my stomache. My legs and thighs aren’t as bad because I walk a lot. But my stomache is what I call a “train wreck”. My back and hips are really suffering from the skin hanging and pulling all day and night. If this stuff works as good as everyone says it does, I would love to be a tester and give it a try. I’m sure my back would love some relief. Thank You in advance.

  44. I read about this particular treatment in Dr. Perricone’s book on a patient who had the same type of red, irritated skin as I do but still needs help with aging skin. (I’m of Irish and Swedish decent so very fair skin, blue eyes and red hair.) I have found a proudct that works with my sensitive skin that is aging. I desperately need something that will help calm my skin down and help with the sagging jawline and fin wrinkles around the mouth and chin.

  45. Love Perricone products! I’m 43 and starting to see the effects of sun damage and aging. Please sign me up.

  46. I am 58 years old and I have spent a small fortune this past year on anti-aging products in which none have helped my appearance. I am so confused as what to buy and I’m wasting money I can’t afford to spend. I can’t afford a face lift and if I could I have reservations about doing so due to getting messed up. I just wish for once I could use a product and actually see results….I believe companies are targeting baby boomers and making mega bucks off their products that aren’t producing results for us. While researching top ingredients in anti aging products I ran across your product…..if I could test this product and see the results as explained,my broken spirit would mend. It is depressing to buy and buy and never see results. Please help!!

  47. I have Asthma and COPD so I always have dark circles and bags under my eyes and look tired even when Iam not. Iam 53 years old and Iam looking for a product such as yours to help my outlook on life. I also live on a fixed income so the upscale products are out of my reach. I want to feel good about myself inside as well as outside.

  48. I would very much like to be a tester. Since the loss of my Husband Its been avey hard life me . I can sure use something to make me feel good about myself again. Thank you

  49. I am 37 years old n have used so many different products and none of them seem to work…..I would luv to try this product cause botox scares me….