Discover the Wrinkle Prevention Power of Alpha Lipoic Acid Cream

Just because the body gets older, does not mean it has to look older. By following an anti-inflammatory diet and using effective treatments, you can restore your skin to a smoother, more youthful appearance.

One way to do this is to start an anti-aging regimen that includes the key science alpha lipoic acid (ALA). ALA can be taken in supplement form or used in topical applications. This article’s focus is on the topical form.

Read on to learn how alpha lipoic acid cream can work to improve your skin’s condition:

How Alpha Lipoic Acid Cream May Help Prevent and Reverse Signs of Aging

To understand how alpha lipoic acid cream works, it is helpful to first understand what causes wrinkles.

One cause of wrinkles is free radical damage. Free radicals are naturally formed molecules that are missing an electron. In order to obtain stability, these molecules seek electrons from the body’s cells. In doing so, they not only damage the cells of the body, but they create new free radicals. In the case of the skin, free radicals take an electron from the collagen molecules in our skin, resulting in damaged collagen and thus, discoloration and loss of elasticity.

When free radicals damage a cell, they also cause inflammation since an enzyme in the free radical damage process produces arachidonic acid. Arachidonic acid is oxidized and produces inflammation, while the inflammation produces more free radicals. Inflammation also plays into aging and can be triggered by a variety of external factors such as excess exposure to UV radiation and cigarette smoke. Inflammation of the skin encourages the formation of lines and wrinkles, as well as other skin conditions.

Alpha lipoic acid cream can help treat and prevent free radical damage and inflammation because of its antioxidant and anti-inflammatory properties. Antioxidants are important because the body employs them to fend off free radicals. Antioxidants work by providing the necessary electron to the free radicals, thereby preventing them from damaging a cell membrane in the first place.

Anti-inflammatory alpha lipoic acid has the ultimate antioxidant power in that it is both water- and fat-soluble. This means it’s a universal antioxidant so it can fight free radicals in any part of a cell as well as enter into the space between cells. Alpha lipoic acid also gives more staying power to other antioxidants, like Vitamin C.

Alpha lipoic acid is also anti-inflammatory in that it can stop the activation of certain transcription factors, which in turn helps prevent the cell from producing pro-inflammatory chemicals that damage the cell. Conversely, alpha lipoic acid cream triggers a helpful transcription factor, AP-1, allowing AP-1 to turn on the production of other collagen-digesting enyzmes. These enzymes digest only damaged collagen, which results in the decreased appearance of wrinkles and scarring.

Finally, alpha lipoic acid cream prevents glycation, a process involving the attachment of sugar to proteins. Glycation is a problem because the proteins become crosslinked, which means they cannot move freely, resulting in loss of skin’s elasticity. Alpha lipoic acid cream helps by allowing the sugar to be better metabolized in the cell, preventing this buildup, and ultimately, sagging skin. Alpha lipoic acid cream may even reverse sugar damage that has already occurred. Although alpha lipoic acid is helpful in preventing glycation, it is no substitute to a healthy, anti-inflammatory diet involving less sugar intake.

Perricone Alpha Lipoic Acid Cream Products

Alpha lipoic acid is available in a variety of Perricone treatments. Perricone Face Finishing Moisturizer, rich in texture, is an alpha lipoic acid cream also formulated with DMAE and Vitamin C Ester. These other anti-aging sciences work synergistically with alpha lipoic acid to help firm skin’s appearance and decrease fine lines and wrinkles.

Another alpha lipoic acid cream to consider is bestseller Advanced Face Firming Activator, which also includes skin firming DMAE. In addition, Advanced Face Firming Activator is formulated with Sodium Hyaluronate, which helps lock in moisture and renew skin’s suppleness.

Which of these Perricone alpha lipoic acid cream products do you prefer? Tell us in the comments section below for a chance to win one!

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34 Comments • Please comment below


  1. I would like to try your products but i am not sure i am 32 years old and my skin is fine except for some fine lines on my forehead and a few expression wrinkles around my eyes ( not that visible) should i start on the ALA or should i wait for a few more years? thank you/

  2. I have wrinkles in my forehead, dark circles and wrinkes muy eyes, and wrinkes around my mouth and chin. Please what do you recommen.

  3. I would love to try your products…although I don’t look too old for my age, I have noticed that I do look older. (I’m 47). I would love to see my face look like it did when I was in my late 20′s. I feel like my skin looks dull!

  4. I’m 58 and have been using this product for two years. People always comment on how great my skin looks and ask me what product I’ve been using.

  5. I have tried many products and spent alot of money. I would love to be a tester for you and see if your worth spending my money.

  6. Oh your products sound wonderful. I’d love to test and review as well on my blog. I’ve read nothing but great things about them.


  8. I have nevr heard of this product so I would definitely like to becom a tester

  9. I have never heard of this product so I would definitely like to try it

  10. under a lot of stress so anything that helps fight free radicals would be great!

  11. Would love to be a Perricone tester. Thanks for these great products and this opportunity.

  12. I would love to try Dr. Perricone’s products. My skin is not too bad, but nothing seems to make a difference

  13. I would like to try this product because Ive suffered for many years with acne, and felt like nothing could help. Ive heard great things about this product so far.


  15. I’ve heard about the benefits of alpha lipoic acid and I would like to test it …I would like to try your brand.

  16. I would love to be a Perricone Tester!

  17. I would like to become a tester.

  18. have heard great things about your products have various skin types in family and we would all like to be testers

  19. I have been using this for years. I’m 60 and when I tell people I’m a great grandma their month falls open. I wouln’t use anything but Perricone.

  20. Would love to test your products!

  21. As a physician, I have heard some amazing things about your products from my patients, but I have yet to try them myself. Keep up the good work!

  22. My face breaks out intermittently with pimples. Sometimes, they are small,irritating bumps. Other times, they are large knots under my skin. I am looking for anything to stop these painful breakouts. I would love to be a Perricone product tester!

  23. I’m experiencing menopause and my skin is changing very quickly. I’ve tried so many things and I am really quite anxious. Please help! I would love to be a tester

  24. I am in my mid 30′s and I am noticing my skin not looking as young as it use to. I would love to test your product(s) and perhaps promote them..Thanks for the chance..

  25. I’ve heard alot of good things about the Perricone products, and would love to try them!

  26. Thank you for the opportunity to become a Perricone MD product tester. You put a lot into the study of what is right for our health and our skin, and you give very generous discounts. I could become a customer for life with true and positive results from using your products. When something works good and is healthy for me, I become an ambassador for the great product and a loyal customer. I look forward to hearing from your company about becoming a product tester. Thank you for the dedicated quality of your products. ~ Andrea M.

  27. I can use all the help I can get to look younger. Please allow me to be a tester.


  28. Alpha Lipoic is my new favorite word! I’d love to be a tester. My skin is perfect for testing. It’s sensitive, yet when something works (as has been the case for many of your products)…it works!

  29. I want to try your products I saw your products in Qvc I believe since then I want to test it so bad, so I can help my african American women to give it a try I serve in a church that have a large group of black women

  30. I want to try your products I saw your products in Qcv I believe since then I want to test it so bad, so I can help my african American women to give it a try I serve in a church that have a large group of black women

  31. I would love to test your products! I had gotten some samples a long time ago, and I love your products!

  32. Heard so much about your products and would love to give them a try! Please sign me up…

    Thank you!

  33. It’s soooo hard to determine how these products work (don’t work) w/o TRYING them out FIRST. So, of course, I would love to be a tester – Perhaps my sensitive agin skin would be a good subject for you. merci

  34. I would love to test your products. I have never tried this brand before but have heard good things about it. Sign me up!!