Alpha Lipoic Acid: Proper Dosage Keeps You Safe

Dr. Perricone has said, “Alpha Lipoic Acid (ALA) has long been one of my favorite nutritional supplements. If I were to list all vitamins for healthy skin, this one would be first.” To get the maximum benefit from this supplement, it’s important to know and abide by the correct dosage.

To ensure safety and efficacy with all medications, treatments, and supplements, it is important to follow the specific dosage guidelines. For most treatments, if you use less than the recommended dosage, the effects are likely to be minimal and disappointing.

However, using too much of many treatments or drugs can have dangerous results for your body. Although no life-threatening side effects have been associated with high doses of alpha lipoic acid (ALA), it is still a very potent substance. Thus, for optimum results, it is crucial to follow all instructions on the supplement bottle and to consult a physician.

This article will discuss:

No prescription is necessary for ALA in the United States, so it is readily available to anyone who wants to take steps toward radiant skin. ALA is found naturally in many foods including red meat, spinach, peas, and broccoli; however, the amount of this superstar antioxidant in a single pill is nearly 1,000 times greater than any food. Supplements usually range from 30 to 100 milligrams per pill. Depending on expectations and desired efficiency, a higher dosage can be administered with few side effects.

Fore more on ALA, watch this video:

Dr. Perricone’s ALA supplement is administered as two 50mg pills twice daily for a total of 100 milligrams of ALA. It provides a simple way to harness ALA for healthier skin and cell protection.

Other essential ingredients contained in this supplement include vitamin E(15 IU), Biotin(200mcg), High-GLA flaxseed powder(100mg) and Bioperine(5mg) – a patented black pepper extract. These high quality supplements are free of sugar, starch, sodium, yeast, milk products, preservatives, and any artificial dyes or coloring.

The Perricone MD supplement should be taken with meals:

  • First at breakfast or lunch
  • And then another at night with dinner

Although some research has shown that ALA is better absorbed on an empty stomach, one possible side effect of ALA is stomach irritation. Thus, Dr. Perricone recommends always taking the supplement with meals.

Skin elasticity and tone can also benefit from ALA administered as a topical cream, cleanser, or toner. One such product is the Advanced Face Firming Activator. Not only does this powerful product treat cheeks, foreheads and chins, Dr. Perricone recommends gently applying the Activator to the neck and behind the ears. These are often ignored places where skin tends to lose elasticity.

Another ALA-containing Perricone product with important dosage directions is the Skin Clear Toner. This product treats problem skin and uneven tone while still being gentle enough to avoid drying out skin. However, everyone’s skin is different, and some skin is more sensitive than others. Dr. Perricone recommends using this toner one to three times daily and to decrease application if dryness becomes a problem.

Besides listening to a physician and paying attention to how different products affect your skin, it is important to follow a regimen that is formulated to suit your skin type. Equally important is recognizing how supplements affect your whole body. Developing this awareness of your body is essential as you begin your journey to healthy, beautiful skin.

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26 Comments • Please comment below


  1. i am just going over my allergies, and i see i need alpha lipoic acid. i also would like to be a tester for your productsbefore i buy. i shall certainly eat more broc…thanks vera

  2. Would love to be a candidate to test your products. I have recently read your book the Wrinkle Cure. Very informative.

  3. I would LOVE to become a product tester, indeed!

  4. I would love to become a tester.

  5. [...] ALA is both water and body fat soluble, meaning it may be absorbed by all of your areas of the body.If you're searching for a secure, easy way to increase your anti-aging treatment beauty regimen, tak…betacarotene, among other things, put together to build up fewer facial lines and lower existing [...]

  6. I am very interested in enhancing health with natural organic foods and supplements. I am the only one in my family who is not on prescription medicatons.

  7. I recently purchased The Wrinkle Cure book & I’m fascinated with all the information. I’m on my way to fabulous skin! Im 35 & i have still have great skin. I would love to be a tester & maintain my look well into my 50′s. Thanku

  8. I’ll give it shot.

  9. I have followed Dr. Perricone for many years with all his advise for many things. I have very dry skin and have used the eye cream, moisturizer and cleanser. I am very interested now in trying the Anti-Inflammatory diet, instant lift and Etc. I trust Dr. Perricone and all his research. I would love to become a Dr. Perricone tester. Thank you

  10. Im a 58 year old male who tried a few anti-inflammatory supplements that Dr. Perricone suggested when I happened to 1st see him on PBS while channel surfing. I purchased and took those supplements and with remarkable results. He had no financial interest in my purchase as they were purchased as he suggested at my local Health food store and his appearance on PBS was without compensation. What more can you say about a healthcare professional who truly concerned about the health and well being of all of America. Thank You.

  11. I am 24 years old and would love to become a tester..

  12. I am interestedin becoming a tester for Dr. Perricone’s cosmetics. My skin a extremely sensitive. I have not found a product to date that agrees with me. Your product might be my final safe haven.

  13. I am wondering about the safety of alpha lipoic acid in someone with a history of atrial fibrillation. Does alpha lipoic acid increase risk for tachycardia and atrial fibrillation? I was gng to start taking it as part of a slow carb diet plan along with green tea flavanols, garlic extract and policosanol. Is this safe. Does anyone have information? Thanks. MC

  14. I am a very young looking 75 year old. Doctors I have not seen before come in room to see me and say they must be in wrong room. They leave and come back in after determining that I am in fact the 75 yer old. It is a compliment since doctors see elderly persons all day long.
    My beauty regimin is very simple. I have been using Cindy crawfords products for over 2 years but don’t especially like the feel of products on my skin. Seems a little dry. I would like to be a tester for your products ( for women senior citizens)
    1 problem I have (not consistently)is brown spots and I can almost determine when they come by how tired I am along with some nausea.Have had this for years I am in good health thank you for your consideration
    Sharon Gerloff

  15. I am a 60 yr old female NZ Maori (now residing in Brisbane Australia), that is an indigenous person of NZ.I am keen to become a tester of your products obviously for my own benefit although more importantly from your angle if not already done I would provide a perfect platform to test your amazing sounding products to add to your already impressive research. Please let me know how this can happen by replying to my email provided. I look forward to hearing from you in the near future…….Regards, Rozelle

  16. “Dr. Perricone’s ALA supplement is administered as two 50mg pills twice daily for a total of 100 milligrams of ALA.”

    Er . . .I’m glad you are not prescribing anything more toxic for me yet! Don’t you think that two 50 mg pills twice daily comes to 200 mg? So, what IS the correct recommended dosage?

  17. I am a big advocate of natural vitamins, foods, etc and feel that God has blessed me with a very strong immune system. I eat well, exercise and take several natural supplements. I am a pastors wife and so am in front of people constantly who ask me what type make up I use, who does my hair, etc, etc. Just goes along with the job description!! Lol… I could defiantely be an advertisement for your product….but very honestly….cannot afford the cost of them. I am in my 50′s and most people say they cant believe it….but who knows? Everything is in perception.
    Anyways, feel free to contact me re: being a tester.
    Thanks & God bless!

  18. I have been taking ala to help reduce severe nerve pain caused from a back injury. I have recently become very interested in ala skin benefits as well, and would love to be a product tester! I turn 50 soon and have tried hundreds of products all promising great results in skin tone, firmness, eveness, wrinkle reduction etc. I have had very positive results with the nerve pain issue. Needless to say, any skin care products with ala and all the other impressive ingredients sparked my interest. I came across your web site and was so impressed with all the ingredients listed as well as their individual benefits. I would be honered to be a product tester!!!

  19. I used Dr. Perricones’s products and supplements several years ago and had great results! I was also following his diet and even had two people tell me I had beautiful skin…the first time in my life! I’ve had problems with my health the last few years; undetected central hypothyroidism, removal of C5 vertebrae, pelvic reconstruction…and unfortunately I’ve gotten back to my old bad eating habits. I’ve also recently lost my job of 14 years so I can’t afford the products now. I am 55 and have problems with adult acne, scaring, rosacea, perioral dermatitis, uneven skintone, chin stubble, and a few wrinkles. I would love to be a product tester! If the products can help my skin, they can help anyones! Thank you!

  20. Hello. I am always looking for skin and health products that are trustworthy and effective. I would be delighted to help test items from time to time.

  21. Dr. Perricone is a doctor we all wish we could visit. I am heading into my thirties and I’m starting to see some changes in my skin. I have always protected myself with an SPF from a young age but alas, gravity alway finds away to catch up. I love Dr. Perricone’s products and if I could afford it, I’d buy his whole line (supplements included)!If given the opportunity to become a tester, I’d be thrilled to help myself and to assist others in the process.

  22. I suffer from cystic acne and I also have wrinkles (as everyone does)and a uneven skin tone. I would love to become a product tester as I would be a perfect example if something actually worked for me!

  23. I am very interested in being a product tester. I have over 15 years experience in cosmetics and look forward to being on the forefront of product development.

  24. I am a former (young baby boomer age)nurse who has also intensively studied herbal and alternative medicine modalities for the past 20 years. I have read two of Dr. Perricone’s books and parts of several other of his materials, have been applying information gleaned from them with positive results, and now find myself very eager to try some of his actual products. Affected by the economy, however, in the form of being “down-sized” out of a job, I would find it particularly helpful and timely to become a product tester…and am excited to have discovered that suggestion here on the website!
    Thank you!

  25. I’ve never used Dr. Perricone’s products, but am very excited about them after seeing him on TV tonight (8/4/09) in Atlanta. I’m a baby boomer and want to look – and feel – 30 again with the help of Dr. Perricone. I would love to be a product tester.

  26. With all of the VERY confusing information out there on supplements, I am so glad to have Dr. Perricone’s easy to understand articles. I would never take supplements from another source before looking up what Dr. Perricone has to say about them first!