Acyl Glutathione
Dr Perricone’s best selling treatment, Acyl-Glutathione, utilizes his patent pending formula for this revolutionary anti-aging product. While addressing the general signs of aging, it also targets the signs of accelerated skin aging, like creases.

Creases occur where you have existing wrinkles, when the body is depleted of essential nutrients. In addition to diminishing creases, it will also improve skin tone, combat extreme dryness, diminish pore size, and tighten and firm skin.


    After 30 days of use:

  • - 93% experienced an increase in the natural radiance of their skin.
  • - 93% saw a reduction in the appearance of skin sagging.
  • - 90% saw a reduction in the appearance of eleven lines.
  • - 90% reported an increase in the tightness and firmness of skin; and in skin resiliency and elasticity.
  • - 90% saw improvement in the overall youthfulness of their skin and felt more confident about their skin.

What is the secret of Acyl-Glutathione?

Dr. Perricone identified Glutathione, during years of anti–aging research, the body’s “master antioxidant”, as a critical nutrient in slowing the aging process. Dr. Perricone patented a stable form called Acyl-Glutathione to help combat the visible signs of accelerated aging, such as creases, deep expression lines, thinning skin and loss of firmness.


Recent reviews


“I am 35 years old with 2 young kids and a busy household…I care about my skin and want to maintain it. I recently purchased this and have been using it at night only. I use cold plasma first and then this on top. My skin looks and feels amazing. My skin appears lifted, it feels more firm and lessens the appearance of my wrinkles. I use other products in the morning on top of my cold plasma but I think this product is better.”

“I would buy this product again and again. It’s a magic cream, just massage on face and neck the creases disappear! I love it and all Perricone ‘s products”

“I use Acyl Glutathione twice a day after I wash my face. It is absorbed quickly and has no smell. It has made a difference in my deep creases on my forehead and my marionette lines in only two weeks!”


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4 Comments • Please comment below


  1. I would like to try the Acyl-Glutathione deep crease serum and the Acyl-Glutathione eye lid serum. I have deep creases on the side of my mouth and one deep crease in between my eyebrows pretty bad. I have loose skin on my eye lids which makes my eyes look saggy.

  2. I have read so many great reviews, I would love to start giving mine as well.

  3. I have begun my Perricone regimen with Formula 15 and the Face finishing moisturizer, but would love to try the Acyl glutathione treatment to correct forehead creases and expression lines. I want to avoid harsh injections that paralyze my expressions, but also want to improve my skin and regain a more youthful look. I would love to try this product as part of my Perricone prescription!

  4. I would love to try your products!!!